Cyano Acetic Acid
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Cyano Acetic Acid

Huihuang Chemical

Cyano Acetic Acid
Specifications

HS Code

503557

Name Cyano Acetic Acid
Chemical Formula C3H3NO2
Molar Mass 85.06 g/mol
Appearance White crystalline solid
Odor Pungent
Melting Point 66 - 68 °C
Boiling Point 265.8 °C
Density 1.325 g/cm³
Solubility In Water Soluble
Pka 2.47
Flash Point 160 °C
Packing & Storage
Packing 500g of Cyano Acetic Acid packaged in a sealed, corrosion - resistant plastic bottle.
Storage Cyano acetic acid should be stored in a cool, dry, well - ventilated area, away from heat and ignition sources. Keep it in a tightly closed container to prevent contact with moisture and air. Store it separately from oxidizing agents, bases, and reactive metals to avoid chemical reactions. This helps maintain its stability and ensures safe storage.
Shipping Cyano Acetic Acid is shipped in tightly - sealed containers, often drums or carboys. It must be transported in accordance with hazardous chemical regulations, ensuring proper ventilation and separation from incompatible substances during transit.
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Cyano Acetic Acid Cyano Acetic Acid Cyano Acetic Acid
General Information
Historical Development
Cyanoacetic acid is also an organic compound. Its origin can be traced back to the past. At the beginning, scholars gradually came into contact with this substance in the study of chemistry. The early preparation method was very simple and the yield was quite low.
Time has passed, and science and technology have advanced. Chemists have worked tirelessly to improve the preparation technique. New methods have been developed, and the yield has increased, and the quality is also excellent. Its application has been widely involved in various fields. In the production of medicine, it is a key raw material; in the production of pesticides, it is also indispensable.
Looking at its historical evolution, from the ignorance of initial knowledge to the ease of use, all rely on the diligence of chemists. This substance has advanced with the times, gradually developing its key capabilities in the field of chemistry, and has become an important member of the chemical industry.
Product Overview
Cyanoacetic acid is also an organic compound. Its color is pure, like a crystalline body, with a specific smell. It is often used in various fields of chemical industry due to its chemical properties.
Its preparation method is formed by several chemical reactions. With specific raw materials, following a suitable process and fine operation, this product can be obtained.
Cyanoacetic acid plays a pivotal role in the organic synthesis industry. It can be used as a raw material for the synthesis of many drugs and dyes. With its structural characteristics, it endows the product with different properties. And in the preparation of some fine chemical products, it is also indispensable and contributes a lot to the progress of chemical technology.
Physical & Chemical Properties
Cyano Acetic Acid (Cyano Acetic Acid) is an organic compound. It is active and acidic, because it contains a cyanide group and a carboxyl group. At room temperature, it is a crystalline solid, white in color and irritating.
Cyanoacetic acid has a melting point of about 90 ° C and a high boiling point of about 260 ° C. This characteristic makes it solid or liquid at a specific temperature environment. Its solubility also has characteristics, and it can be soluble in common solvents such as water and ethanol.
Chemically, cyanide groups can undergo many reactions, such as hydrolysis to form carboxylic acid derivatives; carboxyl groups can be neutralized with bases to form salts. Due to its physicochemical properties, cyanoacetic acid is widely used in the field of organic synthesis and is a key raw material for the preparation of many important compounds.
Technical Specifications & Labeling
Cyanoacetic acid is also an organic compound. Its industrial production method is made by the reaction of chloroacetic acid and sodium cyanide.
Process specification: Raw materials chloroacetic acid, sodium cyanide, etc., must meet the specific purity. The reaction is carried out at a suitable temperature and pressure in the reactor, stirring evenly to ensure that the reaction is complete. After the reaction is completed, it is refined through the steps of neutralization, filtration, concentration and crystallization.
Product identification (product parameters): The appearance is white crystalline, the melting point is about 76-78 ° C, the content is not less than 98%, and the moisture is less than 0.5%. Woven bags lined with plastic bags, the net weight of each bag is 25 kg. Store in a cool, dry place, heat, moisture, away from tinder, heat source.
Preparation Method
The preparation of cyanoacetic acid
Fu cyanoacetic acid is also an important agent in organic synthesis. The preparation method, raw materials and production process are the key.
The first raw materials are chloroacetic acid, sodium cyanide, etc. commonly used. Dissolve chloroacetic acid in an appropriate solvent and gradually add sodium cyanide. The solvent needs to have good solubility and stability. The reaction step is to control the temperature at a suitable temperature, often in a certain range, so that the two can fully react.
The reaction mechanism is the principle of nucleophilic substitution. Chloroacetic acid has high activity of chlorine atoms, and the cyanyl group in sodium cyanide has nucleophilic properties. The cyanyl group attacks the carbon of chloroacetic acid, and the chlorine atom leaves to form cyanoacetic acid
The production process also needs to be considered, and the stirring rate and reaction time are all important. If stirred well, the reaction speed and uniformity will be obtained, and the yield will be good if the time is appropriate. In this way, cyanoacetic acid can be prepared and used in the field of organic synthesis.
Chemical Reactions & Modifications
Taste the way of chemical industry, is wonderful in change, related to the transformation of substances and the improvement of properties. Today, Cyano Acetic Acid is a matter of this. Its chemical reaction, or combination with other substances, or self-decomposition, all have a fixed number. In the past, all the sages explored its reaction mechanism, and observed that when it met with alkali, it would produce a different kind of salt, which is also a sign of this reaction.
If you want to improve its performance, you must evaluate the situation and observe the changes in its environment. If the temperature and humidity are different, the rate of reaction and the quality of the product are different. Therefore, in order to improve its performance, it is necessary to control the temperature and humidity, adjust the proportion of the reactants, and make the reaction tend to be perfect. In this way, the cyanoacetic acid can be used to the best of its ability, and it can help a lot in the chemical industry. It is also in line with the wonders of creation and the ability of chemistry.
Synonyms & Product Names
Cyano Acetic Acid (Cyano Acetic Acid) is also a chemical product. Its name is limited to the world, and there are many reasons for it. Or cyanoacetic acid, and there are also those with cyanoacetic acid. These general names all refer to the same thing. The name of the product sold by the market is a little bit, but it is not the same. Cyanoacetic acid, the purpose of use, is in the field of synthesis, and it is an important raw material. The name of the product is known to all, and it is not called by any name. It is so that the image of the name of the same product will not cause confusion in the market.
Safety & Operational Standards
Cyanoacetic acid product safety and operating specifications
Cyanoacetic acid is an important raw material in the chemical industry. It is active and plays a key role in many chemical reactions. However, it also has certain risks, so it is essential to know its safety and operating standards.
First of all, the rules of storage. Cyanoacetic acid should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent danger. The storage place should be equipped with suitable materials to contain leaks. Do not mix with oxidants, alkalis, etc., because of its interaction, or cause violent reactions, endangering safety.
As for the operation, the operator must be professionally trained and act in strict accordance with the operating procedures. There should be good ventilation facilities in the operation room to reduce the concentration of harmful gases. The operator needs to wear appropriate protective clothing, protective gloves and goggles to prevent contact and injury.
During handling, it must be handled lightly. Do not damage the container or cause material leakage. If a leak occurs, the personnel in the contaminated area of the leak should be quickly evacuated to a safe area and quarantined, and access should be strictly restricted. Emergency personnel must wear self-contained positive pressure breathing apparatus and anti-acid and alkali work clothes. Do not let leaks come into contact with combustible substances. For small leaks, a mixture of sand, dry lime, or soda ash can be used to collect in a dry, clean, covered container. For large leaks, a dike or pit should be built to contain them, and transferred to a tanker or special collector by pump, recycled or transported to a waste disposal site for disposal.
Furthermore, if you accidentally come into contact with cyanoacetic acid, you must not know the first aid method. If you come into contact with the skin, you should immediately remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention. If you come into contact with the eyes, you need to lift the eyelids, rinse with flowing water or normal saline, and seek medical attention in time. If inhaled by mistake, you should quickly leave the scene to a fresh place to keep the respiratory tract unobstructed, such as breathing difficulties, give oxygen, stop breathing, immediately perform artificial respiration and seek medical attention. Those who take it by mistake, drink enough warm water, induce vomiting, and seek medical attention.
In short, the safety and operating standards of cyanoacetic acid are related to the safety of practitioners and endanger the smooth production. Everyone should follow it carefully and not slack off.
Application Area
Cyano Acetic Acid (Cyano Acetic Acid) is also an important chemical product. Its use is not good, and it has extraordinary performance in many fields.
In this field, cyanoacetic acid can be synthesized into a variety of high-efficiency raw materials. With its base, it can be used to prevent diseases and diseases, and it can be used for crops in the field, ensuring the hope of harvest.

In terms of production, it also has important functions. It can be used as a key ingredient in the synthesis of dyes, helping to research and develop a cure for diseases and save people, relieve the pain of patients, and promote the progress.
In addition, in the synthesis of dyes, cyanoacetic acid is also indispensable. Its characteristics can make the color and fastness of dyes better, and it can be used for printing and dyeing to increase the beauty of the product.
Therefore, cyanoacetic acid plays an important role in the application fields such as oil, gas, and dyes, and promotes the development of all industries.
Research & Development
Description of the research and use of cyanoacetic acid
In today's world, science and technology are changing day by day, and chemical substances are of great help to all industries. Cyanoacetic acid is an important chemical material.
At the beginning of the research, various sages focused on exploring the method of its preparation. After repeated trials, they gradually achieved good results. Under suitable conditions and with suitable materials, the cyanoacetic acid can be prepared. The method is good, and the yield is also increased.
As for the use, cyanoacetic acid is used in the field of medicine and is an essential material for the production of various medicines. For example, some antibacterial agents and analgesic drugs depend on it. In the industry of pesticides, it is also indispensable. It can help to produce insecticides and herbicides to ensure the safety of crops.
And it is also useful in the genus of dyeing, weaving and fragrances. It can help dye the color of the product to be even and the quality of the fragrance to increase. From this point of view, cyanoacetic acid is of great value in industry and people's livelihood. Researchers are still working hard, hoping to expand its new use, improve its quality, and meet the needs of the world to promote the eternal progress of its industry.
Toxicity Research
Nowadays, there are cyanoacetic acid products, which are very important for the study of its toxicity. Cyanoacetic acid is an organic acid with a cyano group. Its toxicity should not be ignored.
After testing, cyanoacetic acid may be able to release cyanogen ions in the body, which is a highly toxic thing. Cyanogen ions can block the operation of the respiratory chain of cells, causing the cells to not get enough energy, and the vitality is exhausted.
It has been tested in animals, fed with cyanoacetic acid, and it is seen that their behavior is abnormal, or there are convulsions and listlessness. And their organs are also damaged, especially the liver and kidneys. This shows that cyanoacetic acid is quite toxic.
When cyanoacetic acid is used in industry and agriculture, it is necessary to be cautious to prevent it from leaking and harming life, and to protect the environment and personal safety.
Future Prospects
In today's world, cyanoacetic acid has great potential in the field of chemical industry, and its future prospects are still promising.
Cyanoacetic acid can be used as an essential material for organic synthesis, and is widely used in the fields of medicine, pesticides, and dyes. In today's world, the development of medicine is rapid, and the need for special compounds is increasing. The way of pharmaceutical synthesis involved in cyanoacetic acid may open up new horizons. In the field of pesticides, green and efficient pesticides are the general trend, and cyanoacetic acid may be the key to research and development, helping to form new agents, protecting agricultural production and maintaining ecology.
And the progress of science and technology is not endless, new synthesis methods, process optimization or continuous emergence. Make cyanoacetic acid more productive, better quality, and lower cost. In this way, the more competitive it is in the market, the wider the field of application. In the future, it is expected to see it emerge in the fields of emerging materials and other fields, adding bricks and mortar to the rise of chemical industry, developing infinite possibilities and opening up new chapters.
Frequently Asked Questions
What are the main uses of Cyano Acetic Acid?
Cyano Acetic Acid (Cyano Acetic Acid) has a wide range of uses. In the field of organic synthesis, its role is crucial.
First, it is a raw material for pharmaceutical synthesis. The preparation of many drugs depends on its participation. For example, when synthesizing some antibacterial drugs, cyanoacetic acid can be used as a key intermediate. Through a series of delicate chemical reactions, the complex molecular structure of the drug is gradually constructed, which helps to improve the efficacy of the drug against pathogens and protects the health of the people.
Second, it is used in the manufacture of pesticides. In agricultural production, pesticides are related to the harvest of crops. The pesticides that cyanoacetic acid participates in the synthesis can effectively resist the invasion of crops by pests and diseases, ensure the strong growth of crops, maintain the stable output of agriculture, and ensure the sufficient supply of food.
Third, it also has extraordinary performance in the dye industry. With its special chemical properties, it can assist in the production of colorful and long-lasting dyes. Fabrics dyed with this dye not only have a beautiful appearance, but also are not easy to fade during daily use and washing, which greatly meets people's needs for the beauty and durability of textiles.
Fourth, it is also indispensable in the field of adhesives. The adhesive prepared by cyanoacetic acid has strong viscosity and can firmly bond objects of different materials together. It is widely used in industrial production, manual production, and many other scenarios, providing strong support for the manufacture and repair of various items.
What are the physical properties of Cyano Acetic Acid?
Cyanoacetic acid is one of the organic compounds. Its physical properties are worth exploring.
Looking at its shape, under normal circumstances, cyanoacetic acid is white and crystalline, with a fine texture, like snow falling in the early winter, pure and regular.
As for its melting point, it is about 66 degrees Celsius. When the temperature gradually rises to this point, the originally solid cyanoacetic acid is like ice melting in spring, quietly turning into a liquid state, showing the wonders of the transformation of the state of matter.
In terms of boiling point, the boiling point of cyanoacetic acid is 265.8 degrees Celsius. At this temperature, the liquid is violently churned and turned into a gaseous state, realizing the transformation from liquid to gaseous phase.
Solubility is also an important physical property. Cyanoacetic acid is soluble in water, just like salt melts in soup, evenly dispersed in it, and intermingles with water molecules. In addition, it also has good solubility in organic solvents such as ethanol and ether, showing affinity for different solvents.
Furthermore, cyanoacetic acid has a certain degree of hygroscopicity. Like a sponge placed in the air, it can absorb surrounding water vapor, which affects its own physical state and purity. This property requires special attention when storing and using.
Its density is also a specific value, which affects its distribution and behavior in various systems. It is an indispensable consideration in chemical operation and product design.
What are the chemical properties of Cyano Acetic Acid?
Cyano Acetic Acid (Cyano Acetic Acid) is a genus of organic compounds with unique chemical properties. This substance has a white crystalline appearance and a slight odor. It is soluble in solvents such as water, ethanol and ether.
Among its chemical properties, the acidity is quite significant. The presence of cyano groups enhances the acidity of carboxylic groups. In chemical reactions, protons are easily released, showing acidic properties, and can neutralize with alkali substances to form cyanoacetate. For example, when reacted with sodium hydroxide, sodium cyanoacetate and water can be obtained.
Cyanyl is also a key active site. It has high reactivity and can participate in many reactions. Under certain conditions, the cyanyl group can be hydrolyzed and converted into a carboxyl group to form malonic acid. Or through a reduction reaction, the cyanyl group can be changed to an amino group to expand the structure and properties of the compound.
At the same time, the carboxyl group and the cyanyl group can also participate in the reaction to achieve intermolecular condensation. For example, under the action of a catalyst with alcohols, an esterification reaction occurs to form cyanoacetate. This product is widely used in the field of organic synthesis and can be used as an intermediate in the synthesis of medicines, pesticides and fragrances.
Furthermore, cyanoacetic acid has certain stability. Under conventional environmental conditions, it can maintain its own structure and properties. However, under extreme conditions such as high temperature, strong acid or strong base, its structure will change, triggering various chemical reactions. This balance of stability and reactivity endows cyanoacetic acid with diverse and important applications in organic synthesis.
What is the production method of Cyano Acetic Acid?
The method of making cyanoacetic acid (Cyano Acetic Acid) is different in the past. Common ones include the following.
One is the method of reacting sodium cyanide with chloroacetic acid. First take chloroacetic acid, dissolve it in an appropriate amount of water, and adjust its pH to an appropriate value. Then slowly add sodium cyanide. This process must be handled with caution, because sodium cyanide is highly toxic. When the two meet, they react, and the chlorine atom is replaced by a cyanyl group to produce cyanoacetic acid. After the reaction is completed, pure cyanoacetic acid can be obtained through separation and purification steps. The key to this reaction is to control the reaction temperature and pH. Excessive temperature or improper pH can cause side reactions to occur, affecting the purity and yield of the product.
The second method is to use hydrogen cyanide and glyoxylic acid as raw materials. In the presence of a specific catalyst, hydrogen cyanide interacts with glyoxylic acid. The cyanyl group of hydrogen cyanide is added to the carbonyl group of glyoxylic acid to form cyanoacetic acid. The advantage of this method is that the raw material is relatively easy to obtain, and the catalyst can make the reaction conditions milder. However, hydrogen cyanide is also a highly toxic substance, and the production process requires extremely high safety protection. During operation, perfect ventilation equipment and protective measures must be taken to prevent the leakage of hydrogen cyanide and endanger the life and safety of the operator.
The third method is the condensation of acetonitrile and formaldehyde. Acetonitrile and formaldehyde are mixed in a certain proportion, and under suitable catalyst and reaction conditions, the two undergo a condensation reaction to produce cyanoacetic acid. The advantage of this method is that the raw materials are widely sourced and the cost is relatively low. However, the reaction process is more complicated, and the reaction conditions, such as temperature, pressure and catalyst dosage, need to be carefully adjusted to make the reaction proceed smoothly and obtain higher yield and purity of cyanoacetic acid.
All these production methods have advantages and disadvantages. In actual production, the most suitable method needs to be weighed according to factors such as the availability of raw materials, cost, equipment conditions and requirements for product purity.
What are the precautions for the use of Cyano Acetic Acid?
Cyano Acetic Acid (Cyano Acetic Acid) is an important organic synthetic raw material. It has high reactivity and certain dangers. During use, many precautions should not be taken lightly.
Cyano Acetic Acid is corrosive and can cause burns when it touches the skin and eyes. Therefore, when taking it, be sure to wear protective equipment, such as acid and alkali-resistant gloves, protective glasses and laboratory clothes. In case of accidental contact, rinse with plenty of water immediately. If it is serious, seek medical attention immediately.
Cyano Acetic Acid is exposed to heat, impact or exposure to open flames, and there is a risk of explosion. Storage and use should be kept away from fire and heat sources, and smoking should be strictly prohibited. Violent vibration and friction should also be avoided during operation.
It is an organic synthetic raw material, and in the synthesis reaction, the reaction conditions are strictly required. Factors such as temperature, pH, reaction time, etc., all have a significant impact on the reaction process and product purity. Therefore, it is necessary to precisely control the reaction conditions during operation and strictly follow the operating procedures.
Cyanoacetic acid has certain toxicity. It can be harmful to health if inhaled, ingested or absorbed through the skin. The site of use must be well ventilated to prevent vapor accumulation. Experimental waste should not be discarded at will, and should be properly disposed of in accordance with relevant regulations to avoid polluting the environment.
In addition, when using cyanoacetic acid, it is necessary to be familiar with its emergency treatment measures. In the event of a leak, personnel should be quickly evacuated to a safe area, cut off the fire source, and emergency personnel need to wear protective equipment, absorb or clean the leak with appropriate materials, and then dispose of it.
In short, the use of cyanoacetic acid must strictly follow safety operating procedures, strengthen personal protection, and handle waste with caution, so as to ensure personal safety and the smooth progress of the experiment.