Cyanoacetic Acid

Huihuang Chemical

Specifications

HS Code	805698
Name	Cyanoacetic Acid
Chemical Formula	C3H3NO2
Molar Mass	85.06 g/mol
Appearance	Colorless to light-yellow crystals
Odor	Pungent
Density	1.32 g/cm³
Melting Point	66 - 68 °C
Boiling Point	265.5 °C
Solubility In Water	Soluble
Pka	2.47
Flash Point	160 °C
Refractive Index	1.4168 (20 °C)

Packing & Storage

Packing	Cyanoacetic Acid: Packed in 5 - liter containers for secure storage and handling.
Storage	Cyanoacetic acid should be stored in a cool, dry, well - ventilated area away from sources of ignition. Keep it in tightly sealed containers to prevent moisture absorption and vapor release. Store it separately from oxidizing agents, bases, and reducing agents to avoid chemical reactions. Ideal storage temperatures are typically around 2 - 8°C for long - term stability.
Shipping	Cyanoacetic acid is a hazardous chemical. It should be shipped in accordance with strict regulations. Use appropriate containers to prevent leakage, and label clearly. Ensure compliance with safety and transportation guidelines for secure transit.

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General Information

Historical Development

Cyanoacetic acid (Cyanoacetic Acid) is an organic compound. It first appeared in the field of chemistry, which is a sign of scientific evolution. In the past, chemists studied it carefully in the laboratory, with wisdom and ingenuity, to analyze the properties of substances and explore the law of chemical synthesis, so they obtained this cyanoacetic acid.
At the beginning, the preparation method was not perfect, and the output was scarce, which was only recognized by a few researchers. However, with the advance of science and technology, the process gradually changed, and the preparation method became more and more refined, and the output gradually increased. It is used in the field of organic synthesis and has become a key raw material for many reactions. Since its birth, it has undergone countless studies and improvements, leaving a profound impression on the development of chemistry, promoting the continuous progress of the chemical industry and becoming an indispensable part of the history of chemistry.

Product Overview

Cyanoacetic acid (Cyanoacetic Acid) is an organic compound. Its color is pure and clear, liquid-like, and has a stimulating odor. In the field of chemical industry, it has a wide range of uses.
can be used as a raw material for pharmaceutical synthesis, and the preparation of many drugs depends on its participation. For example, in the synthesis of some cardiovascular drugs and antibacterial drugs, cyanoacetic acid is a key intermediate. It is also indispensable in the production of pesticides, which can help to form efficient pesticides and protect the growth of agricultural plants.
Its chemical properties are active, and the cyano group coexists with the carboxyl group, so that it can participate in a variety of chemical reactions. The products derived from it are also increasingly important in the fields of materials science. It is also a widely used and significant compound in the field of chemical industry.

Physical & Chemical Properties

Cyanoacetic acid (Cyanoacetic Acid) is an organic compound. It is active and has unique physical and chemical properties. Looking at its physical properties, at room temperature, it is a white crystal, like frost and snow, pure and delicate. The melting point is moderate, about 90 to 92 degrees Celsius. When heated, it melts and melts into a liquid. It is soluble in water, like salt melts in soup, and can also be dissolved in organic solvents such as alcohols and ethers. If a fish gets water, it is immiscible.
In terms of its chemical properties, the coexistence of cyano and carboxyl groups makes this substance have both characteristics. Cyanide is nucleophilic, and carboxyl is acidic. Therefore, it can participate in many chemical reactions, such as esterification with alcohols and condensation with amines, which can occur. These characteristics make cyanoacetic acid widely used in the field of organic synthesis, and it is an indispensable raw material for chemical production, pharmaceutical research and development, etc.

Technical Specifications & Labeling

Cyanoacetic acid is also an organic compound. The process specification and identification (commodity parameters) of its preparation are related to quality and application, and are of paramount importance.
In the process specification, the choice of raw materials must be pure, and the temperature, pressure and time of the reaction must be fixed. If sodium cyanide and chloroacetic acid are used as the starting point, the reaction should be controlled so that it can be fully combined, and the separation and purification techniques can be repeated to obtain good products.
In terms of identification (commodity parameters), its purity should be high and impurities should be less. The appearance should be white crystals, and the melting and boiling points have constant values, which is the key to determine the merits. And whether its chemical properties are stable or not, it is also necessary to observe the identification in detail for storage and use. In accordance with this process specification and clear identification (commodity parameters), the quality of cyanoacetic acid is guaranteed, and it can be used in the pharmaceutical, pesticide, and dye industries to promote the progress of chemical industry.

Preparation Method

Cyanoacetic acid is also an organic compound. The method of its preparation, raw materials and production process are essential. Chloroacetic acid and sodium cyanide are often used as raw materials and obtained by cyanidation.
First, prepare the solution of chloroacetic acid, control its temperature and concentration. Then, slowly add sodium cyanide and stir it to make a full reaction. Among them, the reaction conditions are very heavy, and improper temperature will cause side reactions, which will affect the yield and purity.
The process of the reaction needs to be closely monitored. After the reaction is completed, the pure cyanoacetic acid can be obtained after post-treatment processes, such as separation and purification. When separating, according to its physical properties, choose the appropriate method, or extraction, or distillation. Purification steps to remove impurities and improve quality.
This preparation method is related to the principles of chemistry and relies on fine operation to obtain good products. It is widely used in chemical and other fields.

Chemical Reactions & Modifications

The anti-modification of cyanoacetic acid in today's research is of great significance. Cyanoacetic acid has special anti-reaction characteristics. In the usual anti-reaction, there are many modifiers. The reaction of the past, or the efficiency is not high, or there are too many side effects.
If you want to modify it, you can analyze it. The presence of cyanyl groups makes the molecular activity high. It can be used as a new catalyst to modify the anti-reaction parts, such as low temperature and low temperature. With a certain medium, the reaction rate rises, and the side reaction is high.
It can also be applied in the reaction environment, and it is suitable for dissolution, so that the molecular effect is good. In this way, the reaction of cyanoacetic acid can be more ideal, the performance can be improved, and it can be used in many fields.

Synonyms & Product Names

Cyanoacetic acid (Cyanoacetic Acid) is also a chemical product. Its name is also widely used. Or cyanoacetic acid, because of its properties of both cyanoacetic acid. In business, there is also a name. There is cyanoacetic acid, which is signified by its name.
The use of this compound is indispensable for the synthesis of diversity. For example, in manufacturing, it can be used as a raw material to assist in the research of materials. In the field, it is also useful, and it can be used for prevention. The complexity of its name and trade name is due to the different industries and different regions. However, what is the name, its original function is probably not good. A person of chemistry must be familiar with its general reputation in order to conduct research, generate knowledge, and operate effectively.

Safety & Operational Standards

Safety and Operating Specifications for Cyanoacetic Acid
Cyanoacetic acid is an important substance in chemical research. Safety and operating standards are the key to its preparation and use.
When preparing, the raw materials used are mostly toxic and dangerous. Such as cyanide, it is extremely toxic and life-threatening if it is not careful. Therefore, the preparation site should be well ventilated and equipped with complete ventilation equipment to disperse harmful gases. Operators must wear professional protective equipment, such as gas masks, protective gloves, protective clothing, etc., to prevent toxic substances from invading.
Store cyanoacetic acid in a cool, dry and ventilated place, away from fire and heat sources. Due to its corrosive nature, storage containers should be corrosion-resistant and well sealed to prevent leakage. Materials of different chemical properties should not be mixed with them to avoid dangerous reactions.
When using cyanoacetic acid, the operation must be fine. Before the experiment, familiarize yourself with the operation process and emergency treatment methods. Operate in a fume hood to reduce the harm of volatile gases to the human body. If it is accidentally splashed on the skin or eyes, rinse with plenty of water immediately and seek medical attention quickly.
Waste treatment should not be underestimated. Waste containing cyanoacetic acid should not be discarded at will. It should be collected in accordance with relevant regulations and handed over to professional treatment institutions for proper disposal to avoid pollution to the environment.
Cyanoacetic acid safety and operating standards are related to personal safety and environmental protection. Researchers should strictly abide by the standards and operate cautiously to ensure the safety of the research process.

Application Area

Cyanoacetic acid is widely used in various fields. In the field of medicine, it is a key intermediate for the production of cardiovascular drugs, vitamin B6, etc. Such as cardiovascular medicine, cyanoacetic acid has been delicately synthesized to become its active ingredient and help blood vessels run smoothly.
In the genus of pesticides, it is used to make insecticides and fungicides. It can produce powerful insecticides, protect farmers and mulberry crops, drive out pests, and ensure a good harvest.
In the dye industry, it is also indispensable. It can be used as a characteristic dye, giving fabrics brilliant colors, bright and lasting color.
And in the manufacture of adhesives, cyanoacetic acid is an important raw material, which makes the adhesive very sticky and is used for bonding various materials, making it strong and durable. It is of great significance in industry and people's livelihood, and has a wide range of uses. It is an indispensable chemical.

Research & Development

The preparation of cyanoacetic acid is related to scientific research and development, and is of paramount importance. The preparation method of the past may have cumbersome and inefficient disadvantages. Today's scholars are trying their best to improve.
In the exploration of the reaction mechanism, the chemical changes are carefully observed to understand the key to each step. During the experiment, carefully adjust the temperature and pressure conditions to ensure a smooth reaction. The raw materials used are carefully selected to achieve the best yield.
After repeated research, the results are gradually emerging. The new method has increased efficiency and reduced cost. And the product purity is better than in the past, and the application path is wider. It can be used in medicine, chemical industry and other fields, and the prospect is quite promising. We should make unremitting efforts to advance cyanoacetic acid products in the path of scientific research and development, and move further and further towards perfection.

Toxicity Research

The toxicity of cyanoacetic acid is related to everyone's well-being and cannot be ignored. Cyanoacetic acid is toxic to a certain extent. It enters the body, or damages the organs, hinders the smooth flow of qi and blood, and causes illness.
Taste all kinds of things and test it, and see that it is in the body of living beings, it can cause all kinds of abnormal conditions. If you touch it carelessly, the skin may be burning, red and swollen, or even ulcerated. If you inhale its qi, the lungs and organs will be invaded, causing coughing and wheezing, chest tightness. If you eat it by mistake, the stomach will suffer, and your life will be endangered.
Therefore, everything about the preparation and use of cyanoacetic acid should be done with caution. Make sure to protect it well and not let it harm people.

Future Prospects

Cyanoacetic acid (Cyanoacetic Acid) is also an organic compound. In today's chemical industry, it has a wide range of uses. Although there has been some development at present, there are still great expectations for expansion in the future.
Looking at its future, it is expected to emerge in the way of pharmaceutical synthesis. Or it can become a key raw material for more specific drugs, for human health and well-being. In the field of material science, it may be able to participate in the creation of new materials, endowing materials with specific properties.
And with the improvement of technology and technology, the yield of cyanoacetic acid may be improved, and the quality can also be improved. Its cost or reduction, the application range can be wider. We should have a warm heart, explore its infinite potential, and wait for the future to shine brightly and add new brilliance to the world.

Frequently Asked Questions

What are the main uses of cyanoacetic acid?

Cyanoacetic acid is one of the organic compounds. It has a wide range of uses, mainly in the following fields.
First, in the field of pharmaceutical synthesis, cyanoacetic acid can be regarded as an important raw material. It is used as the starting material for the preparation of many drugs. For example, when synthesizing some cardiovascular drugs, cyanoacetic acid can be converted into key intermediates through a series of delicate chemical reactions, and then the finished drug with exact curative effect can be obtained. Due to its unique chemical activity of cyanyl and carboxyl groups, it can participate in a variety of organic reactions, providing the basis for the construction of drug molecular structures.
Second, in the manufacture of pesticides, cyanoacetic acid also plays an indispensable role. The synthesis of many efficient pesticides depends on this. Such as some new insecticides, cyanoacetic acid can be given more excellent insecticidal performance and selectivity by ingenious chemical modification and combination. It can change the way pesticide molecules interact with specific targets in pests, enhance drug efficacy, and have relatively little impact on the environment.
Third, in the dye industry, cyanoacetic acid is also useful. It can be used as an important component in the synthesis of specific dyes. With its chemical structure characteristics, it can introduce special chromophore groups or chromophore groups into dye molecules, so that the dyes have a brighter color, higher dyeing fastness, and better light resistance and washing resistance. In this way, it meets the needs of high-quality dyes in the textile and other industries.
Fourth, cyanoacetic acid is widely used as a basic raw material in the field of organic synthesis. It is the starting point for the synthesis of many complex organic compounds. Chemists have constructed a variety of organic molecules with different functions and structures through the ingenious transformation of cyano and carboxyl groups, such as hydrolysis, esterification, addition, etc., laying the foundation for the research and development of organic chemistry.

What are the physical properties of cyanoacetic acid?

Cyanoacetic acid is also a unique chemical property. Its properties are various, and I will come one by one.
Cyanoacetic acid, under normal conditions, is in the form of white crystals, with pure quality and positive color. Its melting degree is between 80 and 84 degrees Celsius. If it is warm to this point, it will melt into a liquid. As for the boiling point, it reaches 283.5 degrees Celsius. When the temperature rises, it is in a gasified state.
This substance has good solubility in water and can be fused with water. It can also be dissolved in organic solvents such as alcohols and ethers. This property makes it convenient for various reactions and applications.
However, cyanoacetic acid is also dangerous. It is corrosive and can hurt the skin if accidentally touched. And the existence of cyanyl groups makes it under specific conditions, or there is a risk of releasing toxic cyanides. Therefore, when taking and storing, it is necessary to be extra careful and strictly abide by regulations to ensure safety.
Cyanoacetic acid has many applications in the chemical industry. Because of its lively chemical properties, it can be used as a raw material for organic synthesis and is indispensable in the pharmaceutical, pesticide, dye and other industries. It can participate in many reactions and build complex organic structures, laying the foundation for the preparation of various products.

What are the chemical properties of cyanoacetic acid?

Cyanoacetic acid is one of the organic compounds. It has many unique chemical properties, let me tell you one by one.
First of all, its acidity, among cyanoacetic acid, because the cyano group is connected to the carboxyl group, the cyano group is a strong electron-absorbing group, which can enhance the acidity of the carboxyl group. Compared with ordinary acetic acid, its acidity is more significant. This property makes cyanoacetic acid in many chemical reactions, can be used as an acidic reagent, participate in specific acid-base reactions, and can neutralize with alkali substances to generate corresponding salts.
In addition, the cyano group nature of cyanoacetic acid is active. Cyanyl can undergo a variety of reactions, such as hydrolysis. Under appropriate conditions, the hydrolysis of cyanyl groups can be converted into carboxyl groups. This reaction has a wide range of uses in organic synthesis and can be used to prepare compounds containing polycarboxyl groups. Nucleophilic addition reactions can also occur. The carbon atoms of the carbon-nitrogen triple bond in the cyanyl group are electrophilic and vulnerable to attack by nucleophilic reagents, thus introducing new functional groups and expanding the structure and function of the molecule.
The carboxyl moiety, in addition to reflecting acidity, can also participate in esterification reactions. When cyanoacetic acid and alcohols are heated in the presence of a catalyst, the carboxyl group dehydrates and condensates with the alcohol hydroxyl group to form cyanoacetate esters. This ester compound has applications in the fields of fragrances, medicine and so on.
In addition, cyanoacetic acid can be used as a bifunctional reagent to participate in the synthesis of many complex organic compounds due to the presence of cyanide and carboxyl groups. By rationally designing reaction routes, organic molecules with diverse structures can be constructed, which plays an important role in the development of organic synthetic chemistry.

What are the production methods of cyanoacetic acid?

There are various methods for making cyanoacetic acid. The most common one is the cyanidation method of chloroacetic acid. This is based on chloroacetic acid, which is combined with sodium carbonate to obtain sodium chloroacetic acid. Then, it is heated with sodium cyanide to form sodium cyanoacetic acid. After acidification, it is finally cyanoacetic acid. The reaction process is orderly, like the ancient rules, one step at a time, and there is a certain number.
Furthermore, there is the method of sodium cyanide and formaldehyde. When sodium cyanide encounters formaldehyde, it initially forms cyanomethanol, and then interacts with formic acid to obtain cyanoacetic acid. In this way, the combination of various things is like the ancient tenon and tenon, which are tightly connected, and each is used for its own purpose.
There are also hydrogen cyanide and glyoxylic acid as the beginning. The gas of hydrogen cyanide, when encountering glyoxylic acid, can also produce cyanoacetic acid under moderate temperature and pressure, with the help of catalysis. This method, such as using clever techniques to control substances, is subtle and delicate.
In addition, there are also those obtained by hydrolysis of cyanoacetamide. Cyanoacetamide is hydrolyzed by hydrolysis, such as cooking butyl to dissolve cattle, according to its principle, and finally cyanoacetic acid is obtained.
These various production methods each have their own strengths and limitations. They need to be used according to the time and place, and the materials are convenient. Only by choosing the good ones can we make the production go smoothly and obtain high-quality cyanoacetic acid.

What should be paid attention to when storing and transporting cyanoacetic acid?

For cyanoacetic acid, it is also an important thing to be transformed. When it is stored and transported, all things must be careful.
First words storage, cyanoacetic acid is active, and it is changeable in case of heat and moisture, so it should be placed in a cool, dry and well-ventilated place. It must be kept away from fire and heat sources to prevent unexpected explosion. Its package also needs to be strictly secured to avoid contact with the air and cause quality change.
As for transportation, cyanoacetic acid is a dangerous chemical, and the transporter should have the corresponding qualifications. On the way, the car must be stable to avoid shock and collision, so as to avoid damage and leakage. In summer, especially to prevent high temperature, it is advisable to choose when it is cold in the morning and evening. And in the transport tool, do not mix other things, especially alkalis, oxidants, etc., to avoid chemical risks.
Furthermore, those who store and transport should be aware of its nature, understand its danger, and receive professional training. If there is any leakage, deal with it quickly according to the plan to ensure environmental and personal safety. In short, when storing and transporting cyanoacetic acid, pay attention everywhere, and be cautious in everything.