Malonic Acid
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Malonic Acid

Huihuang Chemical

Malonic Acid
Specifications

HS Code

522615

Name Malonic Acid
Chemical Formula C3H4O4
Molar Mass 104.06 g/mol
Appearance White crystalline solid
Odor Odorless
Density 1.619 g/cm³
Melting Point 135 - 137 °C
Boiling Point 386.8 °C (decomposes)
Solubility In Water Soluble
Pka1 2.85
Pka2 5.70
Packing & Storage
Packing Malonic acid packaged in 5 - kg bags for easy handling and storage.
Storage Malonic acid should be stored in a cool, dry place, away from heat sources and direct sunlight. It should be kept in a tightly - sealed container to prevent moisture absorption and contact with air, which could potentially lead to oxidation. Store it separately from strong oxidizing agents and bases to avoid chemical reactions. Ensure proper ventilation in the storage area.
Shipping Malonic acid is typically shipped in tightly - sealed containers to prevent leakage. It may be sent in drums or bags suitable for corrosive substances, ensuring compliance with chemical transportation safety regulations during transit.
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Malonic Acid Malonic Acid Malonic Acid
General Information
Historical Development
Malonic Acid, there is an acid. Its history has not been developed, and the source has not been released. Early on, chemists have studied this thing, and its properties have been improved. At the beginning, the method of improving the method is not good, and the amount is very small. However, the month has passed, and the technology has changed day by day, and it has been improved. In the past, it was a poor method, and a good product was obtained. Those who have ingenuity, improve the work, so that the amount of Malonic Acid can be increased, and the product can be improved. Its application in the field of chemistry and use. From the rare use in the past to today, it is indispensable for technology, materials, etc. This is also the outline of the development of its history, and the steps of the technology of transformation are not good, and the contribution is not great.
Product Overview
Malonic Acid (Malonic Acid) Product Overview
Malonic acid is also an organic compound. Its formula is\ (C_3H_4O_4\), which is white crystalline at room temperature and has hygroscopicity.
This product has a wide range of uses. In the field of organic synthesis, it is a key raw material. It is often used to make medicines, fragrances and polyester resins. For example, in pharmaceutical manufacturing, it can be used to synthesize a variety of drugs to help heal diseases. In the production of fragrances, it can add a unique flavor to fragrances.
The method of preparation is mostly obtained by hydrolysis of cyanoacetic acid. The hydrolysis process requires controlled conditions to ensure yield and purity.
When using it, you should also pay attention. It is corrosive and may come into contact with human body or cause injury. During operation, it is advisable to follow safety procedures and take good protection. In this way, malonic acid can be used well and contribute to the development of various industries.
Physical & Chemical Properties
Malonic Acid is also a matter of transformation. Its materiality can be studied in detail. Its color is often dark, such as crystalline water, which is clear and transparent. Smell it, the taste is light, and there is no strong taste. As for its solubility, it is soluble in water, because its molecules have a specific attractive force in water molecules, so it can be mixed with water.
It is also interesting to consider its chemical properties. Malonic Acid is acidic, and it can cause the reaction of neutralization and the reaction of the biological phase. The carboxyl group in its molecule is the source of its acidic nature. This acid is useful in the field of synthetic chemistry and is often used as an important raw material, as it can provide a specific function, so that the reaction can follow a specific path, and the process of synthesis can be promoted.
Technical Specifications & Labeling
There are Malonic Acid products today, and its technical specifications and identification (commodity parameters) are the key. Looking at its color, it should be pure and free of impurities, just like the whiteness of new snow, without the slightest peculiar color mixed in. Its taste should be elegant, without pungent odor, and pleasant to smell.
In terms of its quality, it must be uniform and stable, without agglomeration or precipitation. To measure its purity with precision, it should reach a very high standard, and the impurity content must be minimal. And its chemical properties should be stable under conventional environments, without easy changes. In the
logo, the parameters of the product must be clear, such as the proportion of ingredients, physical characteristics, etc., all of which must be accurate, so that the user can see at a glance, and then use it properly according to its characteristics to achieve the best results. In this way, the essence of the technical specifications and labels of Malonic Acid products can be met.
Preparation Method
In Malonic Acid, it is also important to transform the product. If you want to do it, the raw material is very important in the production process. The raw material is often taken from the phase of the chemical. In the production process, the reverse step should be refined.
At the beginning, make the phase raw materials mixed according to a specific method and place them in an appropriate environment, so that they can be transformed and reversed. The reverse effect, the degree of resistance, the force and other components should be controlled to ensure the reverse effect.
However, when the reverse effect is completed, the separation, lifting and other steps can be removed, and the Malonic Acid can be obtained. The catalytic system cannot be ignored, and the catalytic effect of the synthesis can be accelerated and the reverse effect rate can be improved. In this way, according to this method, Malonic Acid can be obtained.
Chemical Reactions & Modifications
Malonic Acid is also a matter of transformation. Its transformation and inversion are worth exploring. In the past, the inversion of this thing was caused by Gacoso.
In its inversion, the inversion is slightly different, and the effect is different. The degree of change, or the amount of difference, can make its inversion direction and the quality of the object change.
If you use a certain method, you can get a thing for the first time, and then you can complete the inversion of the environment, the transformation is sudden, and new things come out. This is all due to the subtlety of the transformation and the action of molecules, which is instantaneous.
If you want to understand the transformation of Malonic Acid, you must investigate the inversion of its inversion, and use different methods to study the reason for its transformation. Only in this way can we know how it works, and in the field of transformation, we can add a wonderful solution, so that it may be greatly used in work, engineering, and engineering in the future.
Synonyms & Product Names
Malonic Acid, Chinese name malonic acid, in our field of chemical research, its trade name has been investigated.
Malonic acid is also known as malonic acid, which is its same name. Its trade name is also known as malonic acid. This chemical product, its characteristics, plays an important role in the process of multi-transformation and counter-engineering.
Our research needs to clarify the difference between its product name and the product name. The name of malonic acid is often found in ancient books, and the source of its transformation is malonic acid. And the product name varies depending on the home and the use.
This identification of the same product name is conducive to our accurate grasp of its characteristics and uses, and can play an important role in the fields of chemical synthesis, chemical research, etc., making our use of malonic acid more mature and efficient.
Safety & Operational Standards
Code of Safety and Operation for Malonic Acid Products
Malonic Acid is also a chemical substance, which is useful in experiments and industrial matters. However, if you want to ensure safety and operation compliance, you must have its own style.
All operations involving Malonic Acid, be sure to read its safety data sheet carefully. The nature, hazards and protection methods of this sheet are the basis for safe operation. Handling this object must be in a well-ventilated place. If it is in an occluded place, its volatilized gas will gather and not disperse, or it will harm the operator's body. If it is used in experiments, use a fume hood as the key to quickly disperse the poisonous gas and not stay in the room.
The operator's hands must be covered with protective gloves. Malonic Acid may hurt the skin, causing redness, swelling and pain. Therefore, it can be protected with chemically resistant gloves to reduce damage. And the eyes also need to be protected. Wear safety eyepieces to prevent it from splashing into the eyes and damaging the eyesight.
The storage of Malonic Acid also has its own rules. When placed in a cool, dry place, avoid fire and heat. If it is near a fire source, it may cause danger of burning; in a humid place, it may change. And it should be stored separately from other things, especially strong oxidants, strong alkalis, etc. Because of its liveliness, it may react violently and endanger safety.
If you accidentally touch it, rinse it with plenty of water quickly. Those who touch the skin should seek medical treatment according to the situation; those who enter the eyes should rush to the medical office after rushing, and there should be no delay. If there is a leak, cut off the fire source first to prevent the danger of ignition and explosion. Small leaks can be adsorbed by sand, vermiculite and other substances, and then properly disposed of after collection; large leaks need to be contained and cleaned up by professional methods to ensure that the environment is clean.
In short, the safety and operation of Malonic Acid must abide by norms and cannot be slack off. The operator is always cautious, so that everything can go smoothly and there is no safety problem.
Application Area
Malonic Acid, or Malonic Acid, has its unique effect in various application fields. In the field of medicine, it can be used as a raw material for drug synthesis. In some medical medicines, malonic acid participates in the reaction to form the required chemical structure and help the drug to exert its efficacy.
In the chemical field, malonic acid can be used to prepare special polymers. Artisans use its characteristics to make the polymerization reaction proceed according to a specific path, resulting in materials with special properties, either tough and durable, or with special chemical stability.
In agriculture, malonic acid-related products can be used as plant growth regulators. Farmers can adjust the growth rhythm of plants, promote their strong growth, or increase their resistance to stress, resist pests and diseases and harsh environments.
Malonic Acid is used in many application fields such as medicine, chemical industry, agriculture, etc., as a key to open many practical ways.
Research & Development
Malonic Acid is also a chemical substance. I am researching it, hoping that it will be beneficial to its research.
At the beginning, explore its properties, study its properties, and know its ability to be used in anti-chemical. With the method of precision, improve its degree of melting and boiling, and its solubility in liquid.
Times, study its synthesis method. It is a common way, or an improved method, or a new way. Hope to obtain efficient and effective synthesis, so that the amount of energy will increase and the cost will be reduced.
Furthermore, study the field of Malonic Acid. It is a raw material that can be produced; it is used in chemical industry, or chemical products, plastics, etc.
Our researchers, unremitting exploration, make the research of Malonic Acid step by step, use it for the benefit of the people.
Toxicity Research
Study on the toxicity of malonic acid products
The toxicity of malonic acid products is related to the health of people's livelihood and the safety of material use. Malonic acid has many applications in chemical production and pharmaceutical development, so it is essential to study its toxicity in detail.
According to a series of experiments, if malonic acid is ingested orally, it can cause digestive system disorders in animals. In light cases, it may cause vomiting and diarrhea, and in severe cases, it may damage the function of organs. And long-term micro-exposure may also cause chronic diseases.
It is irritating to the skin and mucous membranes. When exposed, it often causes the skin to be red, swollen, and even ulcerated. If it enters the eyes, it will damage the eyes and cause vision impairment.
However, the occurrence of toxicity is often related to the dose and contact time. Reasonable control of the amount and careful protection can reduce the harm. Therefore, when using malonic acid products, strictly abide by the procedures and prepare protective equipment to protect personal safety and avoid toxicity.
Future Prospects
Malonic Acid is also a thing of transformation. I am researching it, and I am going to develop it before it is developed, and my heart is going. Its power in the way of transformation and synthesis is extraordinary. It may be able to open up new research and development channels, making the world better and saving people. It is also expected to reveal a new angle in the field of materials, and the new nature of the materials will make it more delicate. Not yet, or it may be possible to integrate many cutting-edge technologies, such as the research and development of smart materials, and life is as convenient. The road ahead may be difficult, but we researchers must adhere to the original intention, study the situation, and promote the research of Malonic Acid, in order to meet the future development and make its effectiveness available to the world.
Frequently Asked Questions
What are the main uses of malonic acid?
Malonic acid (Malonic Acid) has a wide range of main uses. In the field of chemical industry, it is often used as a raw material for organic synthesis. It can be used to prepare various esters because of its carboxyl group activity, which can be esterified with alcohols to form malonic acid esters. Malonic acid esters are of great significance in organic synthesis and can be derived from a variety of compounds through many reaction paths. For example, when synthesizing barbiturates, malonic acid esters are the key starting materials.
In the field of medicine, malonic acid and its derivatives are also widely used. Some compounds containing malonic acid structure have certain biological activities, or can be used as drug intermediates. After further chemical modification and modification, drugs with specific pharmacological effects can be made to treat various diseases.
In the field of materials science, malonic acid also plays a role. It can participate in the synthesis of certain polymers, and through its special chemical structure, it imparts different properties to the polymer, such as improving the solubility and thermal stability of the material, so as to meet the requirements of different application scenarios.
In addition, in analytical chemistry, malonic acid can be used as a complexing agent. Due to the fact that there are groups in the molecular structure that can coordinate with metal ions, they can form stable complexes with specific metal ions, which is helpful in the separation and detection of metal ions, and helps to accurately analyze the content and morphology of metal ions in various samples.
What are the physical properties of malonic acid?
Malonic acid, also known as malonic acid, is an important organic compound. Its physical properties are unique, and let me tell you one by one.
Malonic acid at room temperature and pressure appears as a white crystalline state, like fine snow powder, with a pure texture. Its crystal structure is regular and orderly, which makes malonic acid stable to a certain extent.
Looking at its melting point, it is about 135.6 ° C. When the temperature rises to this point, malonic acid will gradually melt from solid to liquid like ice and snow in the warm sun, starting a journey of other forms. The boiling point is 386.8 ° C. At this high temperature, malonic acid turns into curling steam and disperses in the air.
Malonic acid is easily soluble in water, just like a fish entering water. In water, it can closely embrace water molecules to form a uniform dispersion system. Not only that, it also shows good solubility in organic solvents such as ethanol and ether, as if it can coexist harmoniously with various solvents.
Smell, malonic acid does not have a strong pungent smell, only a slight smell, compared with many highly irritating chemicals, it can be said to be mild.
The density of malonic acid is about 1.619 g/cm ³, which is slightly thicker than that of water. This density characteristic makes it have a unique impact on the density of the system when participating in chemical reactions or mixing substances.
In summary, malonic acid's white crystalline appearance, specific melting point and boiling point, good solubility, mild odor, and unique density together outline its physical properties, which play a key role in many fields such as organic synthesis, medicine, and chemistry.
What are the chemical properties of malonic acid?
Malonic acid (Malonic Acid) is an organic compound with the molecular formula\ (C_ {3} H_ {4} O_ {4}\) and the simple structural formula\ (HOOC - CH_ {2} -COOH\). This substance has many chemical properties and is used in many fields.
Malonic acid is acidic because its molecule contains two carboxyl groups\ (- COOH) \), which can ionize hydrogen ions in water\ ((H ^{+})\) , so it is acidic. Its acidity is stronger than acetic acid, and partial ionization can occur in water, such as:\ (HOOC - CH_ {2} -COOH\ rightleftharpoons HOOC - CH_ {2} -COO ^ {-} + H ^{+}\) 。 Because of its acidity, malonic acid can neutralize with bases. Taking sodium hydroxide as an example, the reaction is as follows:\ (HOOC - CH_ {2} -COOH + 2NaOH\ rightarrow NaOOC - CH_ {2} -COONa + 2H_ {2} O\) to generate the corresponding malonate and water.
Malonic acid also has the properties of esterification reaction. Under the condition of concentrated sulfuric acid as catalyst and heating, malonic acid can be esterified with alcohol. For example, when reacting with ethanol, the chemical equation is:\ (HOOC - CH_ {2} -COOH + 2C_ {2} H_ {5} OH\ xrightarrow [{\ Delta}] {concentrated sulfuric acid} C_ {2} H_ {5} OOC - CH_ {2} - COOC_ {2} H_ {5} + 2H_ {2} O\) to form diethyl malonate and water. This esterification reaction is quite important in the field of organic synthesis, and diethyl malonate is an important intermediate in organic synthesis.
When heated, malonic acid is easily decarboxylated. When heated to a certain temperature, a carboxyl group in its molecule will be removed in the form of carbon dioxide\ (CO_ {2}) \). The reaction is as follows:\ (HOOC - CH_ {2} -COOH\ xrightarrow {\ Delta} CH_ {3} COOH + CO_ {2}\ uparrow\) to form acetic acid and carbon dioxide. This decarboxylation reaction is of great significance in the study of organic chemistry mechanisms and some organic synthesis pathways.
Malonic acid can also participate in substitution reactions. Because the hydrogen atom on the\ (- CH_ {2} -\) in the molecule can be replaced by other atoms or atomic groups under specific conditions. For example, under appropriate catalyst and reaction conditions, halogen atoms can replace hydrogen atoms on\ (- CH_ {2} -\) to generate halogenated malonic acid derivatives, which can be used in organic synthesis to introduce specific functional groups and expand the structure and properties of organic compounds.
What are the methods for preparing malonic acid?
Malonic acid (Malonic Acid), there are several ways to prepare it. First, cyanoacetic acid is used as raw material and obtained by hydrolysis. First, take an appropriate amount of cyanoacetic acid, put it in the reaction kettle, add an appropriate amount of water and catalyst, and slowly heat it up. Under suitable temperature and pressure, the cyano group is hydrolyzed into a carboxyl group, which is a key step. The cyanoacetic acid of cyanoacetic acid meets water and the catalyst, and after chemical reaction, it is gradually converted into the carboxyl group of malonic acid. After the reaction is completed, the pure malonic acid can be obtained by separation and purification.
Second, chloroacetic acid is used as the starting material. First, chloroacetic acid is reacted with sodium carbonate to form sodium chloroacetate. This reaction requires precise control of the proportion of materials and the conditions of the reaction, and attention should be paid to temperature and pH. Chloroacetic acid and sodium carbonate are mixed in a certain proportion, and the reaction is stirred at a specific temperature to obtain sodium chloroacetate. Then, sodium chloroacetate is reacted with sodium cyanide to form sodium cyanoacetate. This step of the reaction needs to be carried out in a safe environment, because sodium cyanide is highly toxic. Finally, sodium cyanoacetate is hydrolyzed to obtain malonic acid. When hydrolyzing, factors such as temperature and catalyst should also be paid attention to to so that the reaction can proceed smoothly and the purity of the product can be guaranteed.
Furthermore, diethyl malonate is also used as a raw material for preparation. Diethyl malonate can be converted into malonic acid through hydrolysis and decarboxylation. Diethyl malonate is placed in a suitable reaction system, hydrolyzed into monoethyl malonate is added with a hydrolyzer, and then decarboxylated to obtain malonic acid. In this process, the conditions of hydrolysis and decarboxylation are very important, and the temperature and reaction time are all related to the yield and purity of the product. Different preparation methods have their own advantages and disadvantages, and should be selected according to the actual demand, availability of raw materials, cost and other factors.
What are the precautions for malonic acid in storage and transportation?
Malonic acid is also a chemical substance. During storage and transportation, many matters must be paid attention to.
When storing, the first environment is heavy. It should be placed in a cool, dry and well-ventilated place. Because of its easy deliquescence, if it is in a humid place, it may cause quality changes. And the temperature should also be suitable, too high temperature, or the instability of its chemical properties, which will affect its effectiveness.
Furthermore, the choice of container is crucial. Corrosion-resistant devices must be used to avoid chemical reactions with the container and damage its essence. Seal must be tight to prevent contact with air, causing it to oxidize or absorb moisture.
As for transportation, stability comes first. Pack light and unload lightly. Do not subject it to violent vibration and collision, otherwise the package may be damaged and malonic acid will spill out.
The transportation environment should not be ignored, and it should be kept dry to avoid water and wet gas. If it is transported for a long time, it is necessary to check regularly during the transportation to see if the packaging is damaged and the quality is not changed.
In addition, the transporter must be familiar with the nature and precautions of malonic acid, and know the countermeasures in the event of an accident. In this way, when storing and transporting malonic acid, its quality can be guaranteed and its safety can be guaranteed.