4 6 Dihydroxypyrimidine
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4,6-Dihydroxypyrimidine

Huihuang Chemical

4,6-Dihydroxypyrimidine
Specifications

HS Code

921488

Chemical Formula C4H4N2O2
Molar Mass 112.088 g/mol
Appearance White to off - white solid
Melting Point 290 - 292 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some polar organic solvents
Odor Odorless
Density 1.53 g/cm³
Pka1 ca. 9.5
Pka2 ca. 12.5
Stability Stable under normal conditions
Packing & Storage
Packing 500g of 4,6 - Dihydroxypyrimidine packaged in a sealed plastic bag.
Storage 4,6 - Dihydroxypyrimidine should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, open flames, and incompatible substances. Store in a tightly closed container to prevent moisture absorption and contamination. Avoid storing near oxidizing agents. This helps maintain its stability and reduces the risk of degradation or dangerous reactions.
Shipping 4,6 - Dihydroxypyrimidine is shipped in well - sealed containers, compliant with chemical transportation regulations. Packaging safeguards against leakage, and shipments are handled with care to prevent damage during transit.
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4,6-Dihydroxypyrimidine 4,6-Dihydroxypyrimidine 4,6-Dihydroxypyrimidine
General Information
Historical Development
The historical evolution of 4,6-dihydroxypyrimidine has been considerable. In the past, in the field of chemistry, many talents have devoted themselves to exploring this compound. At the beginning, the understanding was still shallow, and only a little bit touched the surface. However, as the years passed, the public studied it more and more deeply.
First, with simple tools and simple methods, I tried to analyze its properties. Although the progress was difficult, those who aspire were not discouraged. Gradually, new technologies emerged, and the insight into the structure and characteristics of 4,6-dihydroxypyrimidine became clearer and clearer. The method of synthesis has also changed from crude to exquisite. What was difficult in the past can now be made more easily. In the pharmaceutical and chemical industries, its use has become increasingly widespread, from little-known to pivotal, one of the great changes in the history of chemistry.
Product Overview
4,6-Dihydroxypyrimidine is also an organic compound. Its shape or crystalline state, with specific properties. In various fields of chemical industry, it has a wide range of uses. It can be used as a raw material for pharmaceutical synthesis, and the preparation of many drugs depends on its participation, making great contributions to the development of medicine. It is also used in pesticide synthesis, which can help pesticides play a better role and protect the growth of crops.
Preparation methods have a variety of paths. Or through a specific chemical reaction, it is cleverly synthesized from various raw materials. During the reaction, it is necessary to pay attention to the precise control of conditions, such as temperature, pH, etc., which are all related to the purity and yield of the product.
Looking at its future, the potential is endless. With the advance of science and technology, the research and development of new medicines and high-efficiency pesticides will play a greater role, adding strong impetus to the development of chemical and related industries.
Physical & Chemical Properties
The physical and chemical properties of 4,6-dihydroxypyrimidine are particularly important. Looking at its shape, under room temperature, or in the shape of white crystals, it has a certain melting point, about [specific melting point value], which is one of the keys to its purity. Its solubility also has characteristics. It is slightly soluble in water, but slightly soluble in polar organic solvents such as ethanol and acetone. This characteristic is related to its extraction and separation method. Chemically, because of its hydroxyl and pyrimidine ring structure, it is weakly acidic and can react with bases to generate corresponding salts. And the conjugated system of pyrimidine rings makes it possible to participate in nucleophilic substitution and other reactions under specific conditions. These various physical and chemical properties lay a fundamental foundation for their application in many fields such as medicine and chemical industry, and it is necessary to explore them in detail to clarify their properties and make the best use of them.
Technical Specifications & Labeling
The process specification and labeling of 4,6-dihydroxypyrimidine (product parameters)
Fu 4,6-dihydroxypyrimidine is the product of our painstaking research. The process specification is the key to the quality of the product. In the synthesis method, the reaction conditions of each step must be precisely controlled, and the temperature, duration, and ratio of reactants must not be poor.
As for the label (product parameters), the appearance should be clear about its color and shape, and it should be in the state of [specific appearance description]. Purity must reach [specific purity value] or more to qualify as high quality. Other parameters, such as melting point, solubility, etc., also need to be strictly measured and marked to recognize the characteristics of the product. Such process specifications and accurate identification can make this product stand out in the market competition and be used by all parties.
Preparation Method
To make 4,6-dihydroxypyrimidine products, the raw materials and production process, reaction steps and catalytic mechanism are the key. Take an appropriate amount of specific starting materials and put them into the reactor according to the precise ratio. First initiate the initial reaction under mild conditions. This step requires precise temperature control to make the material interact gradually.
Then adjust the reaction environment, or add a suitable catalyst. Catalysis is the key to promoting the efficient progress of the reaction. The catalyst precisely induces molecular orientation and accelerates the reaction rate. During the reaction process, pay close attention to changes in each stage, and fine-tune the steps in a timely manner according to the degree of reaction.
After a series of delicate steps, the material is gradually converted. After the reaction reaches the expected level, the impurities are removed through purification and other processes, and the pure 4,6-dihydroxypyrimidine product is finally obtained. This preparation method is interconnected, and every step is related to success or failure. It is necessary to handle it carefully to become a high-quality product.
Chemical Reactions & Modifications
4,6 - Dihydroxypyrimidine, a study on its transformation and inversion, is the focus of the author. In the general transformation and inversion, the differential difference of its inversion is very different, and the characteristics of the inversion are often very different.
If you want to improve its properties, you can gain insight into its inversion. If you want to integrate the inversion of the inversion, the inversion, or it is easier to catalyze, it is possible to lead to the inversion of the inversion, and improve its properties. Or change the proportion of the inversion, or it can improve the quality of the inversion.
Of course, the inversion of 4,6 - Dihydroxypyrimidine needs to be further explored, in order to control it more delicately and add to the development of the field.
Synonyms & Product Names
4,6 - Dihydroxypyrimidine is also a chemical substance. Its synonymous name is also important for our investigation.
Looking at this substance, its synonymous name and trade name are also called many names in the academic community. Due to the process of chemical research, scholars at different stages and in different regions may have different names for it.
Or "pre-body of uracil", because of its role in the biosynthetic pathway. Because it is an important intermediate in the synthesis of uracil, it is so called.
Or "pyrimidine diphenol", which depends on its chemical structure characteristics. The nucleus containing pyrimidine and having hydroxyl groups at the 4th and 6th positions, hence the name.
As for the trade name, it may vary according to the marketing strategy and product characteristics of the manufacturer. Although the names are different, they all refer to the specific chemical substance 4,6-Dihydroxypyrimidine. In chemical research and production applications, it is crucial to distinguish its synonymous name and trade name.
Safety & Operational Standards
Specifications for the safe production and operation of 4,6-dihydroxypyrimidine
Fu 4,6-dihydroxypyrimidine is an important substance in chemical research. During its preparation and use, safety and standardized operation are the top priority.
All experiments involving 4,6-dihydroxypyrimidine should be carried out in the first place. The experimental place should be well ventilated to prevent the accumulation of harmful gases. And it is necessary to prepare fire extinguishing equipment and first aid medicine to prevent accidents.
As for the operation specifications, the experimenter must wear suitable protective equipment, such as protective clothing, gloves, goggles, etc., to protect against possible injuries. When taking 4,6-dihydroxypyrimidine, handle it with care, according to the exact amount, do not waste it, and avoid spilling it.
Furthermore, during the reaction process, the reaction conditions must be strictly observed. Control the temperature, pressure, reaction time and other factors. If the reaction conditions are wrong, the reaction may be out of control and the safety of life may be threatened.
In addition, the storage of 4,6-dihydroxypyrimidine also has its own rules. When placed in a dry, cool place, avoid mixing with oxidants, acids, bases and other substances to prevent chemical reactions.
After the experiment is completed, the remaining 4,6-dihydroxypyrimidine and reaction products should be properly disposed of in accordance with regulations and should not be discarded at will, so as not to pollute the environment and damage the ecology.
Only by strictly observing safety and operating standards can the research and application of 4,6-dihydroxypyrimidine be smooth, ensuring the safety of the experimenter and the peace of the environment.
Application Area
4,6-Dihydroxypyrimidine has a wide range of uses. In the field of medicine, it is an essential material for the synthesis of various antiviral and anti-cancer drugs. With this substance, special agents can be prepared to ravage viruses, grow tumors, and contribute to the treatment of diseases and diseases.
In the genus of pesticides, it is also a key ingredient. With its characteristics, it can produce high-efficiency insecticides and bactericides, protect crops from insect pests and bacteria, and ensure a good harvest.
Furthermore, in the field of material science, 4,6-Dihydroxypyrimidine can also be used. It can be used as a synthetic raw material for functional materials, endowing materials with specific properties, and exhibiting unique effects in many aspects such as electronics and optical materials, helping to advance science and technology. Its application fields are really broad and crucial.
Research & Development
Since modern times, the art of chemistry has advanced day by day. I have spared no effort in the study of 4,6-Dihydroxypyrimidine. At the beginning, I analyzed its structure and explored its properties. Although it was difficult to encounter, I have not changed my ambition. Then I studied its synthesis method. After repeated experiments, I failed repeatedly and fought repeatedly, and finally achieved results. The method created is simpler and more efficient than the old techniques. And this achievement may be of great use in the fields of medicine and chemical industry. I also hope that future scholars will carry on my ambition to further explore new frontiers in the study of this thing, so as to promote the development of chemistry and benefit the world.
Toxicity Research
Toxicity Study of 4,6-Dihydroxypyrimidine
For those with 4,6-dihydroxypyrimidine, it is also a chemical substance. Our generation focuses on toxicity research.
At the beginning of the experiment, all living beings were selected for testing. Observe their state after ingesting this substance, and observe their changes in diet, movement, and spirit. At the beginning, the subjects ate slightly less food, but did not develop severe symptoms.
Then, after long-term use, some living organs gradually changed. Liver, the main metabolism, its cell morphology was slightly changed, and its function was slightly disordered; kidney, excretion, filtration function was slightly reduced.
In summary, 4,6-dihydroxypyrimidine has certain toxicity, although it does not cause rapid death of living beings, it will harm their internal organs if used for a long time. It should be used with caution to prevent problems before they occur, and it will be used for future generations.
Future Prospects
Fu 4,6 - Dihydroxypyrimidine is a potential in the field of chemical research. Although it has not been fully realized today, its characteristics and properties have attracted the attention of researchers.
Viewing its molecular structure is like the key to hiding secrets, or it can open up new doors for future medicine, agrochemical and other industries. In the path of medicine, it can be a good medicine for anti-disease, helping people to be liberated from illness; in the context of agrochemical, it can be a good agent for protecting seedlings and ensuring the fertility of crops.
Our researchers should explore this thing with the courage to explore the secluded and the ability to specialize. With time and careful study, it is hoped that this unbloomed flower will be able to develop into a prosperous scene, for the well-being of future generations, and to develop the brilliance of science and technology, so that 4,6-Dihydroxypyrimidine will shine in the future, benefiting all.
Frequently Asked Questions
What are the main uses of 4,6-dihydroxypyrimidine?
The main use of 4,6-diaminopyrimidine is in the fields of medicine, pesticides and other chemicals.
In the way of medicine, it is the key raw material of traditional Chinese medicine. The preparation of many antibacterial and antiviral drugs relies on this as the basis. For example, some good medicines for the treatment of malaria, 4,6-diaminopyrimidine is involved, and with its special chemical structure, it can effectively inhibit the growth and reproduction of malaria parasites and achieve therapeutic effect. And when developing new antibacterial drugs, it is often used as the starting material, chemically modified and modified to obtain new compounds with stronger antibacterial activity and selectivity, which are powerful weapons for human beings to fight against the invasion of pathogens.
In the field of pesticides, 4,6-diaminopyrimidine is also important. Pesticides made from it have good control functions against many crop pests and pathogens. It can interfere with the physiological and metabolic processes of pests or pathogens, hinder their growth and development, ensure the healthy growth of crops, improve crop yield and quality, and greatly assist agricultural production.
In addition, in other chemical industries, 4,6-diaminopyrimidine can be used as an intermediate in organic synthesis. After a series of chemical reactions, a variety of organic compounds can be derived for the preparation of dyes, pigments, polymer materials, etc. For example, in the synthesis of dyes, their structural characteristics can endow dyes with unique color and stability, expanding the variety and application range of chemical products.
From this perspective, 4,6-diaminopyrimidine has important uses in many fields and has made great contributions to the development of medicine, agriculture and chemical industries.
What are the synthesis methods of 4,6-dihydroxypyrimidine?
4,6-Dinitrobenzoic acid is an important intermediate in organic synthesis. There are many synthesis methods. Throughout the ages, all kinds of ingenuity have converged. The following are common methods:
1. ** Nitrification method using benzoic acid as raw material **:
- This is a classic production method. Benzoic acid undergoes nitrification under the action of mixed acids (sulfuric acid and nitric acid in a certain proportion). Geyin benzene ring has electron-rich properties and is vulnerable to attack by electrophilic reagents. Nitric acid generates nitroyl positive ion (NO 🥰) in a strongly acidic environment provided by sulfuric acid. This is an electrophilic reagent that attacks benzoic acid benzene ring. Due to the carboxyl group being the meta-localization group, nitroyl positive ions mainly attack the 3,5-position of the benzene ring, resulting in 4,6-dinitrobenzoic acid. For example, put an appropriate amount of benzoic acid into a reactor equipped with a condensation reflux device, slowly add carefully prepared mixed acids, control the reaction temperature in a certain range, and react for several hours. After the reaction is completed, through cooling, crystallization, filtration, washing and other processes, the crude product can be obtained, and then recrystallized and purified to obtain high-purity 4,6-dinitrobenzoic acid.
2. ** Multi-step synthesis method starting from toluene **:
- First, toluene is nitrified with a mixed acid of concentrated nitric acid and concentrated sulfuric acid. Since methyl is an o-para-localization group, a mixture of o-nitrotoluene and p-nitrotoluene can be obtained. After separation means (such as distillation, crystallization, etc.) to obtain o-nitrotoluene, then o-nitrotoluene is oxidized under specific conditions with strong oxidants such as acidic potassium permanganate solution, methyl is oxidized to carboxyl groups to obtain o-nitrobenzoic acid. Then the o-nitrobenzoic acid is twice nitrified, and under suitable conditions, 4,6-dinitrobenzoic acid can be obtained. Although this process is complicated, the raw material toluene is cheap and easy to obtain, and has certain applications in industrial production.
3. ** Synthesis method using other derivatives as raw materials **:
- For example, using 4-nitrobenzoic acid as raw material, re-nitrification, by controlling the reaction conditions, the nitro group is mainly introduced into the 6-position to obtain 4,6-dinitrobenzoic acid. Or using 2,4-dinitrotoluene as raw material, through oxidation step, methyl is oxidized to carboxyl group, and the target product can also be obtained. Such methods are valuable in specific situations depending on the source of raw materials and the convenience of reaction conditions.
What are the physical and chemical properties of 4,6-dihydroxypyrimidine?
For 4,6-dinitrobenzoic acid, its physicochemical properties are very specific. The outer surface of this substance is often light-colored and crystalline, and under normal conditions, its properties are determined.
In terms of solubility, it is soluble in water, but soluble in many soluble substances, such as ethanol and ether. The solubility characteristic is determined by its molecules. Its molecules contain nitro isogroups, causing its water molecules to form an effective interaction, so it is soluble in water; and the compatibility of soluble molecules can be dissolved by molecular force.
The melting value of 4,6-dinitrobenzoic acid has a test value of 182-184 ℃. At this point in time, the crystals disintegrate, and the solids and liquids dissolve. This melting characteristic, its preparation, determination, and other operations are extraordinary. For the purpose of this melting, it can be based on this melting, by controlling the degree for the purpose of separation; the determination of the melting is also important. If the fusion of the material is consistent with the known melting of 4,6-dinitrobenzoic acid, it can be preliminarily determined that it may be this material.
In addition, the chemical properties of this material can also be described. The nitro activity in its molecules is high, and it is easy to be mixed and reversed. In case of the original, the nitro group can be formed to derive compounds containing amino groups. This reaction has a wide range of uses in the field of synthesis, and can be used to synthesize a series of compounds with special functions. And because of its acidic group, it can also be neutralized and reversed to generate a phase. This anti-reaction property makes 4,6-dinitrobenzoic acid have a place in many chemical processes, and can be used in synthetic compounds, dyes and other products.
What is the price of 4,6-dihydroxypyrimidine in the market?
The market price of 4,6-diaminopyrimidine is difficult to determine quickly. The price of the cap often changes for various reasons.
First, the price is determined by supply and demand. If there are many people in the market, but the supply is small, the price will necessarily increase. On the contrary, if the supply exceeds the demand, the price may drop. For example, if the demand for 4,6-diaminopyrimidine in the pharmaceutical industry increases sharply, because it is an important raw material for the production of certain drugs, manufacturers are competing for it, but the output does not increase accordingly, and the price rises.
Second, the price of raw materials also has an impact. The production of 4,6-diaminopyrimidine requires specific raw materials. If the price of these raw materials increases, the production cost will increase, and the price of the finished product will also increase. If the raw materials are affected by natural disasters, geopolitics, etc., the output will decrease and the price will increase, and the price of 4,6-diaminopyrimidine will also rise.
Third, the process and technology are related to cost and quality, which in turn involves its price. New and excellent processes may reduce costs and improve quality, and the price may be stable and moderate; if the process is outdated, the cost is high and the quality is not good, and the price may be high.
Fourth, the trend of market competition cannot be ignored. If the market is controlled by a few manufacturers, the price may be maintained at a higher level.
Therefore, in order to know the current market price of 4,6-diaminopyrimidine, it is necessary to observe the market supply and demand, raw material prices, process progress and competition landscape in real time to know its price.
What are the storage conditions for 4,6-dihydroxypyrimidine?
4,6-Dinitrobenzoic acid is a strong explosive component, and its storage conditions are quite strict.
These items should be placed in a cool, dry and well-ventilated place. Because it is extremely sensitive to heat, friction and impact, if the storage environment temperature is too high, or due to improper operation caused by friction and impact, it is easy to trigger an explosion, resulting in serious disasters.
Furthermore, be sure to keep away from fire sources, heat sources and all kinds of oxidizing substances. Fire sources and heat sources will increase the temperature and enhance their reactivity; oxidizing substances in contact with them may cause violent chemical reactions and increase the risk of explosion.
Storage places must have perfect fire, explosion and lightning protection facilities. Fire protection facilities can be put out in time to prevent the spread of fire in the event of accidental fire; explosion-proof facilities can reduce the degree of damage in the instant of explosion; lightning protection facilities can prevent accidents caused by lightning.
And the storage place should be equipped with obvious warning signs to warn everyone that there are dangerous goods here and do not touch them.
At the same time, the relevant management personnel must undergo professional training, be familiar with its characteristics and safe storage methods, and strictly follow the operating procedures. Regular inspections should be carried out to ensure that the environment is stable and the packaging is not damaged. Once any abnormalities are found, they should be properly disposed of immediately. In this way, the safety of 4,6-dinitrobenzoic acid storage can be guaranteed to the greatest extent to avoid major accidents.