Barbituric Acid
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Barbituric Acid

Huihuang Chemical

Barbituric Acid
Specifications

HS Code

806845

Name Barbituric acid
Chemical Formula C4H4N2O3
Molar Mass 128.087 g/mol
Appearance White crystalline powder
Odor Odorless
Density 1.679 g/cm³
Melting Point 248 °C
Solubility In Water 1.2 g/100 mL (25 °C)
Pka1 4.01
Pka2 12.4
Crystal Structure Monoclinic
Packing & Storage
Packing Barbituric acid, 500g, packaged in a sealed, corrosion - resistant plastic container.
Storage Barbituric acid should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a well - sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from oxidizing agents and other incompatible substances to avoid chemical reactions. Follow all safety regulations for storing this chemical.
Shipping Barbituric acid is shipped in accordance with strict regulations. It's typically packaged in corrosion - resistant containers to prevent leakage. Shipment requires proper labeling, and is often handled by specialized carriers trained in transporting chemical substances.
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Barbituric Acid Barbituric Acid Barbituric Acid
General Information
Historical Development
Barbituric acid is also an important chemical substance. It was first obtained by the German Adolf von Bayer in 1864 by co-heating diethyl malonate with urea. At first, it was only the object of chemical research and was not exposed to the world.
After several years, doctors gradually explored its properties and found that it had a soothing effect on the nerves. Then it was used in medicine as a sleeping and sedative agent. Its effect is remarkable, and it was popular for a while.
However, it has been used for a long time, and its disadvantages are also present. Excessive amounts are dangerous and prone to addiction. It is because the medical community is gradually cautious. However, in the history of medicine, it will eventually leave a heavy pen for future generations to develop new drugs, inspire ideas, identify its advantages and disadvantages, and promote the progress of medicine.
Product Overview
Barbituric Acid is also a kind of thing. Its shape is beautiful, and its nature is also special. When you first obtain it, you can study its nature, make it, and use your mental strength.
This compound has its own uses. In the realm of the world, it can be used as a place for peaceful sleep, so that the god of impatience can be at peace, and those who sleep can sleep. However, if you use it carefully, it will harm your body and endanger your life.
It is also useful in the way of work. It helps to make the opposite of it, and it will become a useful thing.
Study Barbituric Acid, and investigate it deeply, and understand its advantages and disadvantages. Only then can it be used properly, benefit the world, and avoid suffering.
Physical & Chemical Properties
Barbituric Acid is a chemical substance. Its properties are both physical and chemical. As far as physical properties are concerned, under normal conditions, Barbituric Acid is a white crystalline powder, which is difficult to detect and smell. Its melting properties are characteristic, and it is at 245 degrees Celsius. This degree makes it possible to reduce the biological phase under specific conditions.
As far as chemical properties are concerned, Barbituric Acid has a certain degree of acidity, which can generate neutralization and reaction, and generate phases. And its molecules contain specific functionalities, making it valuable in the field of synthesis. It can be used as a raw material for multiplication and reaction, synthesizing a variety of compounds, and has important uses in many fields such as chemistry and chemical industry.
Technical Specifications & Labeling
For the products of Barbituric Acid, process specifications and identification (product parameters) are the key. The process specifications need to follow a precise process, the ratio of raw materials must be accurate, and the reaction temperature and duration should be strictly adhered to the established number, so as to ensure the purity and quality of the product.
In terms of identification (product parameters), the ingredients, characteristics, uses, etc. should be listed in detail. The ingredients are clear, so that users know their quality; the characteristics are fully described, such as characteristics, stability, etc., so that users can make good use of them; and the uses are marked to make them suitable.
Only with rigorous process specifications and accurate identification (product parameters) can the products of Barbituric Acid be praised and used in various applications.
Preparation Method
Barbituric Acid is an important organic compound. The preparation method and the selection of raw materials are crucial. Diethyl malonate and urea are often used as starting materials. When preparing, diethyl malonate is reacted with sodium alcohol first. This step is to activate diethyl malonate to make it more reactive. Then urea is added, and the two are reacted at a suitable temperature. The reaction goes through steps such as condensation. The amino group of urea interacts with a specific group of diethyl malonate. After a series of reaction steps, Barbituric Acid is formed. This preparation process requires strict control of reaction conditions, such as temperature, reactant ratio, etc., in order to improve the purity and yield of the product. The whole preparation mechanism is based on nucleophilic substitution and condensation reactions between organic compounds to achieve the purpose of synthesizing the target product.
Chemical Reactions & Modifications
Barbituric Acid is also a matter of transformation. Its transformation and anti-modification are suitable for those who study it.
At the beginning, study its anti-modification, observe the transformation of the elements, and combine the elements to form this new thing. Its anti-transformation, there is a certain degree of resistance, such as the combination of the elements, there are some parts.
As for the modification, if you want to improve its goodness, or increase its efficiency, or ease it. Those who use ingenuity, apply wonderful methods, or improve it, or add other elements. In this way, the things of Barbituric Acid can have new energy, and can be used in both fields.
To study the chemical and anti-chemical modification of Barbituric Acid, it is the key to the research of Neihua, hoping to obtain new fruits for the benefit of the world.
Synonyms & Product Names
Barbituric Acid is also a chemical product. Its trade name is the same, and it is important for the chemical industry.
In the past, chemists explored this product, and many of them had the same name. For example, "a certain acid" is also named after its characteristics. As for the trade name, it is recognized by the family for its characteristics, and it also takes a general name.
Or because of its stability, it is named "Anhydric Acid"; and because of its action, it is "Sleeping Acid". There are many trade names because of the wide use of Barbituric Acid, which is used in agriculture, chemical industry and other industries. The name of the name is, but it refers to this thing. Those who want to understand it must check the reason for each name, so that they can be transparent.
Safety & Operational Standards
Barbituric acid products, that is, barbituric acid products, are mostly sedative and hypnotic drugs, which are related to the safety of users, so their safety and operation standards are of paramount importance.
All preparations and uses of barbituric acid products must be done in the laboratory or medical institution in compliance. The laboratory should have complete ventilation, fire protection, explosion-proof and other safety facilities to ensure a safe operating environment. In medical institutions, the use and preparation of drugs must strictly follow the established procedures.
When operating, the experimenter must wear professional protective equipment, such as laboratory clothes, gloves, goggles, etc., to prevent the drug from coming into contact with the skin and eyes. The operation of weighing and mixing drugs should be fine and accurate, and the established formula and operation steps should be strictly followed. It must not be changed without authorization. Drug storage should also be exquisite. It should be placed in a dry, cool and ventilated place, away from fire sources and oxidants. Different drugs should be stored according to their characteristics to avoid confusion and reaction.
Use barbituric acid products to treat patients. Doctors should accurately diagnose and use drugs rationally according to the patient's condition, constitution and other factors. Detail the patient's medication method, dosage and possible adverse reactions. During the medication period, closely monitor the patient's reaction and adjust the treatment plan in time.
Discarded barbituric acid products and related wastes must not be discarded at will. They should be properly disposed of in accordance with the regulations on hazardous waste disposal to prevent environmental pollution and endanger public health.
In short, the safety and operation standards of Barbituric Acid products, from preparation, use to waste disposal, must not be lost at every step, so as to ensure the safety of personnel and avoid accidents.
Application Area
Barbituric Acid is a wonderful thing to be transformed. Its application is not easy to use, and it is easy to understand. In the field of knowledge, it is often a recipe for a good sleep. In the past, there were many problems of insomnia, which could be peaceful. It can calm the impatience of the mind and make the body and mind difficult.
It is also an important raw material in the process of synthesis. Help to generate multiple compounds and expand the field of chemical research. In the research of many new technologies, Barbituric Acid needs to be used with caution.
However, it needs to be used with caution. If it is not used properly, it may lead to undesirable results. Therefore, those who use it must observe its characteristics and weigh the pros and cons in order to make good use of it and avoid its shortcomings.
Research & Development
Barbituric Acid is an important chemical compound, which plays a key role in the fields of medicine and chemical industry. We have been focusing on its research and development for a long time.
At the beginning, the exploration of Barbituric Acid only covered the skin, and only its basic chemical composition was known. However, with the deepening of research, many special properties of Barbituric Acid became apparent. In medicine, its derivatives can be used as sedative and hypnotic agents, which can soothe nerves and help patients fall asleep.
The road of scientific research is full of difficulties. In order to improve the performance of Barbituric Acid, we have repeated experiments, adjusted the synthesis method, and changed the reaction conditions. Fortunately, the new derivatives not only have better efficacy, but also reduce side effects.
In the field of chemical engineering, Barbituric Acid and its products are used to synthesize a variety of organic materials, contributing to the development of materials science. Looking forward to the future, we will continue to study it, hoping to shine in more fields and contribute more to human well-being.
Toxicity Research
Taste the harm of poison, even more than the tiger. The toxicity of Barbituric Acid products is the top priority in today's research.
Examine this product carefully, although its nature may have medical ability, but if it is not careful, it will become a disaster. Its entry into the body may be chaotic, disturbing the order of the viscera. At first, I may feel light and fascinated, like an illusion; over time, I will lose qi and blood, become depressed, and the viscera will gradually decline.
Looking at the past examples, those who misuse this product will find it difficult to get up from the couch and life difficult to deal with; the soul of the serious will be scattered, and their lives will go to Huangquan. Therefore, the study of its toxicity must be detailed and deep. It is necessary to explore the cause of its poisoning and the state of poisoning, so as to obtain a way to avoid disasters and protect the well-being of all living beings from its poison.
Future Prospects
Barbituric Acid is an important chemical that has shown unique properties and uses in the past. In the future, its development is very promising.
In the field of medicine, Barbituric Acid derivatives are expected to make breakthroughs in the treatment of neurological diseases. Although current research has made progress, it is not perfect. In the future, it may be able to precisely act on specific neural pathways to provide better therapies for epilepsy, insomnia and other diseases, and help patients get rid of their suffering.
In materials science, this compound also has potential. By adjusting its molecular structure, or it can create new materials with special properties, such as high strength, high toughness and unique optical and electrical properties, which can be used in aerospace, electronic devices and other fields.
Furthermore, in the environmental field, Barbituric Acid-related products may be able to assist in the treatment of pollutants. With its chemical activity, high-efficiency adsorbents or catalysts may be developed to purify the environment and freshen the earth.
In summary, Barbituric Acid has broad future development prospects. If further research is conducted over time, it will surely contribute to human well-being and open a new chapter.
Frequently Asked Questions
What is the chemical structure of barbituric acid?
The chemical structure of carbopic acid is also the key to chemistry, which is related to the properties and properties of many substances.
The structure of carbopic acid has a unique structure. Its core part is connected by a number of atoms in a specific order to form a stable structure. The bonding between atoms, or covalent bonds, are closely connected to make the structure solid.
Looking at its outer layer, there are several functional groups attached to it. This functional group has an extraordinary effect and affects the chemical activity and reaction characteristics of carbopic acid. It is either hydrophilic, which makes carbopic acid have a specific dissolution and dispersion in water; or it is lipophilic, which makes it unique in organic environments.
And the atomic space arrangement of barbioic acid cannot be ignored. This three-dimensional conformation determines the mode of interaction between it and other substances. The shape of the molecule is related to whether it fits the activity check point of other molecules, which in turn affects the process and result of chemical reactions.
The structure of barbioic acid, or the existence of isomers. Although it has the same chemical formula, the atomic connection mode and spatial arrangement are different, resulting in significant differences in its properties. This isomerism phenomenon adds many variables and challenges to the study of barbioic acid.
To understand the chemical structure of barbioic acid, a variety of scientific methods are required. Or use spectroscopy, such as infrared spectroscopy, to detect the vibrations of functional groups in molecules, to reveal their types and environments; or use nuclear magnetic resonance to analyze the state of atomic nuclei in molecules, and to determine the connection and spatial relationship between atoms.
In summary, the chemical structure of Habioic acid is composed of elements such as the connection of atoms, the attachment of functional groups, and the arrangement of space. It is complex and delicate, and it is an important research object in the field of chemistry. It is of great significance for understanding related chemical reactions and developing new substances.
What are the main physical properties of barbituric acid?
Palladium bismuth oleic acid is one of the chemical substances. Its main physical properties are slightly lower.
Looking at its shape, at room temperature, palladium bismuth oleic acid is often in the form of a liquid, with a more viscous texture. It is like an oily fluid. When it flows, it is quite slow, just like a stagnant plaster. It is left standing in the container. It can be seen that its surface is smooth and shiny, like a mirror surface.
As for the color, it is mostly light yellow, with a soft color and no dazzling eyes. It is just like a daisy in the early autumn, elegant and fresh. Its smell, although not rich and pungent, has a unique smell, with a slight fragrance of oil. If you smell it carefully, you can also feel its different taste.
When it comes to density, it is larger than water. If water is used as a reference, palladium-bismuth oleic acid is poured into water, and it will sink to the bottom, just like a stone drop pool, which shows that its mass is heavier than water.
Furthermore, its solubility is also a characteristic. In organic solvents, such as ethanol, ether, etc., palladium-bismuth oleic acid can be moderately dissolved, just like salt in a warm soup, gradually melting in it; however, it is insoluble in water, and it is placed in water, just like oil floating on water, distinct and self-formed.
has melting point and boiling point. Its melting point is relatively low, and it is easy to melt into a liquid in a warm environment; while the boiling point is higher, in order to make it boil and vaporize, a higher temperature needs to be applied, which can be caused by unusual heating.
In addition, the surface tension of palladium-bismuth oleic acid is also considerable. On the surface of the liquid, a relatively tight film can be formed. If you touch it lightly, you can feel that there is an elastic film on the surface, which is not easy to break easily. This characteristic has important implications in many practical applications.
What are the common synthesis methods of barbituric acid?
The common synthesis methods of burbio acid are as follows:
First, the semi-synthesis method using natural products as the starting material. If Gu Zhifang's family does this, or finds natural products with similar structures, according to the theory, with all kinds of exquisite skills, to transform. For example, choose a certain plant essence containing a specific functional group, adjust its structure in a gentle way, and introduce the required groups one by one to achieve the structure of burbio acid. Among these, it is necessary to carefully observe the characteristics of natural products, make good use of their inherent activity check points, and operate with precision to ensure the purity of the product and the best effect.
Second, chemical synthesis method.
1. Taking common organic compounds as the cornerstone, it is constructed by multi-step reaction. For example, it starts with simple hydrocarbons, alcohols, algens, etc. First, a hydrocarbon is substituted with a specific reagent, and key functional groups are introduced, and then the molecular skeleton is shaped by reactions such as addition and elimination. For example, starting with alkenes, adding with hydrogen halides to obtain halogenated hydrocarbons, and then nucleophilic substitution with carboxyl-containing reagents, and then a series of oxidation, reduction and other steps to eventually form primary biolic acid. This process requires a deep understanding of the conditions and mechanisms of various reactions, and precise control of the reaction process to avoid dissimilation and by-products.
2. Metal Catalytic Synthesis. In ancient times, although there were no such exquisite metal catalysts as modern ones, it may be possible to simulate them over time. Today's methods often use transition metals as the catalytic core, such as palladium, nickel, etc. The coupling reaction of alkenyl and alkynyl substrates with suitable reagents occurs under metal catalysis. Such as Suzuki reaction, Heck reaction, etc., with the activation power of metals, carbon-carbon bonds are efficiently constructed, and then the structure of burbiol acid is built. This requires detailed study of the activity and selectivity of metal catalysts, selection of suitable ligands, and optimization of the reaction environment to promote the smooth reaction.
3. Cyclization reaction construction method. If a chain-like compound containing a multifunctional group is used as a raw material, it will undergo intramolecular cyclization. For example, a chain containing carboxyl groups and alkenyl groups, under appropriate conditions, will be added to the molecule to form a cyclization, and then modified to obtain the cyclic structure of Burbiol acid. This requires precise control of the reaction conditions to make the cyclization position and form compatible, and attention should also be paid to the connection of the modification steps after cyclization to achieve the purpose of synthesis.
What are the applications of barbituric acid in the field of medicine?
"Tiangong Kaiwu" says: "The use of medicine for treating diseases is like using soldiers." The use of medicine is related to human life, so it cannot be ignored. Today there is crotonoleic acid, which does have many applications in the field of medicine.
Crotonoleic acid has antibacterial properties. It is often written in ancient books that when poisons are rampant, the reason why certain herbs can heal patients is because of the antibacterial effect of the special ingredients contained. Crotonoleic acid can effectively inhibit the growth of a variety of bacteria in vitro experiments, such as Escherichia coli, Staphylococcus aureus, etc. If this bacteria disturbs the human body, it can cause gastrointestinal discomfort in the light, and life-threatening in the heavy. Crotonoleic acid can block the invasion of bacteria and maintain human health like a good general in ancient times.
Furthermore, it has also made a name for itself in tumor research. "Huangdi Neijing" says: "Those who are strong cut it, and those who are knotted disperse it." Tumors are aggregates in the body. Modern research has found that crotonoleic acid may induce tumor cell apoptosis and inhibit tumor cell proliferation. This effect is like a skilled craftsman dismantling complex objects, gradually disintegrating the evil potential of tumor cells, and providing new ideas for tumor treatment.
Ramba soybean oil is highly acidic, and the Compendium of Materia Medica also says that croton is "hot and toxic". Although it has medicinal potential, it needs to be carefully weighed when used. In ancient times, physicians used medicine, paying attention to monarchs, ministers, and envoys, and croton oleic acid was used as medicine, and it should be the same. It needs to be accurately proportioned and reasonably processed in order to give full play to its length and avoid its toxic harm, so that it can truly benefit the common people in the field of medicine.
What are the precautions in the preparation of barbituric acid?
When preparing croton oleic acid, many things need to be paid attention to.
Selection of the first raw materials. The quality of croton is related to the purity of oleic acid. Choose croton with large and plump grains, positive color and no rot, and it can be a good source. If croton is poor, the oleic acid is impure, or contains impurities, which affects its properties.
The second time is the operation temperature. Boiling croton to get oleic acid, the size and duration of the fire are all about success or failure. If the fire is fierce, croton will be scorched, and the oleic acid will be damaged and of poor quality; if the fire is small, the oil will not be smooth, time-consuming and the yield will be low. When boiled slowly, croton will slowly produce oil, stabilize the temperature, and maintain the quality of oleic acid.
Furthermore, prevent toxicity. Croton is highly toxic, and the operation room must be well ventilated to avoid toxic gas accumulation. Operators should also use protective equipment, such as gloves and masks, to avoid croton and oleic acid from touching the skin and entering the body, which may cause poisoning.
Separation steps are also critical. After croton oil comes out, oleic acid needs to be separated by appropriate methods. Or use filtration to remove residues; or use distillation to improve the purity of oleic acid. The selection method depends on the situation, so that oleic acid is pure.
Storage should not be ignored. After obtaining oleic acid, it should be placed in a cool and dry place and stored in a sealed device. Avoid light and hot topics, avoid oxidation and deterioration of oleic acid, and keep its stability for subsequent use. The preparation of crotonoleic acid requires careful treatment in order to obtain high-quality products.