On the compatibility of adapalene and glycolic acid
The combination of drugs and acids is often related to the effectiveness and skin safety. Today's focus on the compatibility of adapalene and glycolic acid is a major concern in the field of skin care.

Adapalene is a retinoic acid drug, which is often used in the treatment of acne. Its function is to regulate the keratosis of the hair follicle mouth, reduce the secretion of sebaceous glands, and has anti-inflammatory effects, which can improve many symptoms of acne. Glycolic acid is an alpha-hydroxy acid, which is also very popular in the beauty and skin care industry. It can loosen the connection between keratinocytes, promote the shedding of the stratum corneum, accelerate the renewal of epidermal cells, make the skin glow, and help improve uneven skin tone, fine lines and other problems.

However, whether the two can be used together needs to be studied in detail. First, from the perspective of skin tolerance, adapalene itself has a certain degree of irritation to the skin, which can cause dry skin, desquamation, erythema, etc. Glycolic acid is also irritating, especially when the concentration is high. If the two are used together, the skin irritation response may be superimposed, which exceeds the tolerance limit of the skin. Those with delicate skin are more likely to cause discomfort, such as burning, itching and other symptoms. Second, in terms of pharmacological mechanisms, although the two have different targets, one is the main pathological link of acne and the other is keratin metabolism. However, the skin is a whole, and complex physiological processes are interrelated. The combination of the two may have unknown effects on the normal metabolism of the skin and interfere with the skin's own balance regulation mechanism.

Therefore, those who want to use adapalene and glycolic acid must be cautious. Use low-concentration products first, try them on a small area, and observe the skin reaction. If there is no discomfort, then gradually increase the range and frequency of use. It is also advisable to consult a professional dermatologist or beautician, and obtain professional guidance according to the severity of personal skin type and skin problems. In this way, the purpose of skin care can be achieved, and the risk of skin damage can be avoided.