Discussion on the combination of azelaic acid and glycolic acid
All things in the world, in the field of medical skin care, the combination of ingredients and the effect are changeable. Azelaic acid and glycolic acid, the combination of the two is worth further investigation.

Azelaic acid has multiple effects. It can inhibit the synthesis of microbial protein, so it has the ability to inhibit Propionibacterium acne, which is often the culprit of acne breeding. And it can regulate the keratinization of the hair follicle mouth, make the hair follicle mouth unobstructed, prevent sebum deposition, and has significant effect in the treatment of acne. And because it can competitively inhibit tyrosinase, it can reduce melanin synthesis, and then lighten the skin and improve the skin with pigmentation.

Glycolic acid is a fruit acid. Its relative molecular weight is small, and it can quickly penetrate the skin. It can loosen the connection between keratinocytes, make the aging stratum corneum fall off, accelerate the renewal of the skin surface, and make the skin smooth and delicate. And it can stimulate the synthesis of collagen in the dermis, increase skin elasticity, and improve fine lines.

The combination of the two has complementary advantages. Glycolic acid causes exfoliation of the stratum corneum, which increases the permeability of the skin, and azelaic acid is easier to penetrate into the skin to exert its effect. In the treatment of acne, it cooperates with antibacterial and improves keratinization, and the effect is better than that of using it alone. For whitening light spots, glycolic acid promotes epidermal renewal, azelaic acid inhibits melanin, and accelerates the fading of pigmentation.

The combination of For those with sensitive skin, low concentration and small area should be used for the first time, and the scope and frequency of use should be gradually increased. And strict sun protection is required when using, because skin renewal is accelerated and more sensitive to ultraviolet rays.

In short, the combination of azelaic acid and glycolic acid, if used properly, can improve skin problems such as acne and pigmentation, and the effect can be expected; however, it needs to be used reasonably according to individual skin type to avoid harm and seek benefits and obtain the ideal skin care effect.