The method of benzyl alcohol to make benzyl nitrile
The benzyl alcohol wants to transfer benzyl nitrile, which is an important part of organic synthesis. Benzyl alcohol is an aromatic alcohol with hydroxyl groups. To make it into benzyl nitrile, a specific reaction path is required.

The common method is to first react with benzyl alcohol and halogenating agents, such as reacting with hydrohalic acid or halogenated phosphorus, so that the hydroxyl group can be replaced by halogen to obtain benzyl halogen. This step requires appropriate temperature and adaptability to promote a smooth reaction.

After benzyl halogen is obtained, it is mixed with cyanide, often reacted with sodium cyanide or potassium cyanide in a suitable solvent. This reaction is nucleophilic substitution, and the halogen atom is replaced by a cyan

When reacting, the choice of solvent is very critical. Polar aprotic solvents, such as dimethyl sulfoxide, N, N-dimethylformamide, etc., can increase the nucleophilicity of cyanide ions, which is conducive to the reaction. And the temperature and reaction time also need to be precisely controlled to avoid side reactions.

In this way, through these steps, benzyl alcohol can gradually convert to benzyl nitrile, which is a common path for the preparation of benzyl nitrile in organic synthesis.