Method of Synthesis of Cyanoacetic Acid
Those who want to study the synthesis of cyanoacetic acid in ancient times must review all materials and procedures, and strive for delicacy.

Where cyanoacetic acid is synthesized, the choice of materials is essential. First, there are many people who use chloroacetic acid and sodium cyanide as the basis. Chloroacetic acid is active and is the starting point of the reaction. Sodium cyanide, containing cyanide roots, is the key to introducing cyanide groups. When the two meet, they can start the synthesis. However, sodium cyanide is highly toxic, and it must be handled with caution to prevent it from leaking, harming people, and polluting the four borders.

Its method is also to put chloroacetic acid in the kettle first, slow down the lye, and adjust its pH to make chloro This step requires temperature control and speed, so as not to cause excessive drama and cause changes in the material. Then, slowly add sodium cyanide solution, the temperature should be stable, about a certain degree, and stir for a long time to promote its fusion. After the reaction is completed, the product is analyzed, and the cyanoacetic acid is purified by neutralization, extraction, and distillation.

There are other materials as the beginning. For example, diethyl malonate is used as the base, and cyanoacetic acid can also be formed after hydrolysis, decarboxylation, and cyanidation. Although this path is different from before, it is all for efficient and pure production.

If you want to be good at the synthesis of cyanoacetic acid, you must pay attention to the materials and procedures, and study them carefully in order to obtain high-quality cyanoacetic acid to meet all your needs.