The
diethyl malonate (Diethyl Malonic Acid) with diethyl malonate as the core is also an important agent in organic synthesis. Its reactivity can open the door to all kinds of reactions.

Guanfu starts with diethyl malonate, and through the technology of condensation, when it encounters halogenated hydrocarbons, it can produce the extension of the carbon chain. If it combines with primary halogenated hydrocarbons, according to the principle of nucleophilic substitution, the hydrocarbyl is added to the methylene of diethyl malonate to obtain a substituted diethyl malonate derivative. This new product, in an alkaline environment, can be dissubstituted with halogenated hydrocarbons.

And the hydrolysis of diethyl malonate is also very interesting. Under the catalysis of acid and base, the ester group cracks and forms malonic acids. Malonic acid is unstable in nature, decarboxylates when heated, loses carbon dioxide, and leaves an active carboxylic acid structure.

And it is also promising for the construction of cyclic compounds. With suitable reagents and conditions, through cyclization, various cyclic products can be obtained, which makes great contributions to the field of organic synthesis.

Diethyl malonate, with its unique properties and diverse changes, is a sharp edge in the hands of craftsmen in the field of organic synthesis, opening up thousands of possible paths and promoting the progress of organic chemistry.