Discussion on whether glycolic acid and azelaic acid can be combined
Recently, whether glycolic acid (Glycolic Acid) and azelaic acid (Azelaic Acid) can be used together in skin care, everyone agrees and is uncertain.

Glycolic acid is an alpha-hydroxy acid, and its molecules are slender, which can run smoothly through the skin and penetrate into the stratum corneum. With its excellent exfoliation effect, it can quickly disperse and shed aging keratinocytes, and restore a smooth and tender state to the surface of the skin. And it can stimulate the regeneration of collagen, which is effective in improving skin texture and reducing fine lines.

Azelaic acid has unique antibacterial and anti-inflammatory properties, which can effectively inhibit the growth of Propionibacterium acne and reduce inflammation. At the same time, it can also inhibit the activity of tyrosinase and interfere with melanin synthesis, thereby fading pigmentation and brightening skin tone.

As to whether the two can be used together, it needs to be carefully considered. From the perspective of chemical properties, there is no significant compatibility between the two. However, glycolic acid is highly acidic, which may cause short-term tingling, redness and other irritation reactions to the skin; azelaic acid is relatively mild, but some people with sensitive skin may also feel uncomfortable. If the two are used together, it may cause skin irritation to superimpose.

Therefore, the method of combined use should first check the tolerance of the skin. At the beginning of use, you can try it in a small range and at a low concentration. If there is no abnormality in the skin, then gradually expand the use area and increase the concentration. And the frequency of use should start from a low level and be gradually adjusted according to the skin's adaptation. For example, in the initial stage, it can be used once or twice a week, and then if the skin is well tolerated, it can be increased to three to four times a week.

In short, the combination of glycolic acid and azelaic acid may bring many benefits to the skin, but the user must carefully observe the skin's reaction and apply it in a scientific and prudent manner to enjoy the benefits of skin care while avoiding the risk of skin damage.