The Effect of Glycolic Acid on Peridermal Keratosis
Peridermal keratosis is a common skin disease. It is mostly caused by excessive keratosis at the mouth of the hair follicle, resulting in the formation of keratin suppositories at the mouth of the hair follicle, and the appearance is a chicken skin rash. It is preferable to the outside of the upper arm, the extension side of the thigh, etc. Although it does not hinder health, it does affect the appearance.

Glycolic acid has unique functions in improving peridermal keratosis. It is an alpha-hydroxy acid with small molecules and good permeability. It can effectively loosen the connections between keratinocytes, promote the exfoliation of the excessive keratinized stratum corneum, and then improve the blockage of keratosis at the mouth of the hair follicle, making the skin gradually smoother.
< b It can weaken the desmosome connection between keratinocytes, accelerate the metabolism of the stratum corneum, and thin the deposited stratum corneum. The normal stratum corneum replacement cycle is about 28 days, and this cycle is often prolonged in patients with perichial keratosis. Glycolic acid can shorten it, so that new and tender keratinocytes can replace the old ones in time and relieve the symptoms of perichial keratosis.

Furthermore, glycolic acid can stimulate collagen synthesis in the dermis. Moderate application of glycolic acid can enhance fibroblast activity, increase collagen secretion, and improve skin texture and elasticity. Perichial keratosis skin is often rough, and collagen supplementation can make the skin firmer and more delicate, reducing the appearance of the disease.

When using glycolic acid, be careful. Because of its certain irritation, excessive concentration or improper use, it is easy to cause adverse reactions such as skin redness, tingling, and desquamation. Beginners should choose low-concentration products, such as 2% - 5% glycolic acid skin care products, apply a small amount of thin to the affected area, and after the skin adapts, gradually increase the concentration or frequency of use according to tolerance. And during use, be sure to pay attention to skin moisturization and sun protection to prevent dry skin and UV damage.

In short, glycolic acid has great potential for improvement in pericrokeratosis, but rational use is the key. Patients should scientifically apply glycolic acid products according to their own skin type and under the guidance of professionals to achieve the best skin improvement effect.