On the relationship between glycolic acid and psoriasis
Glycolic acid has attracted more and more attention in the field of skin care. However, its relationship with psoriasis is worth exploring.
Today's detailed investigation shows that psoriasis is a chronic and recurrent skin disease characterized by erythema, scales, and itching and pain. The cause of this disease is complex, involving genetic, immune, and environmental factors.
Glycolic acid is an alpha-hydroxy acid. It has unique chemical properties and can participate in the process of skin metabolism. First, it can loosen the connection between keratinocytes, promote the shedding of the old stratum corneum, and make the skin surface smooth and delicate. Second, it can stimulate the synthesis of collagen in the dermis and enhance skin elasticity.
There are various academic opinions on the effect of glycolic acid on psoriasis. It is said that the exfoliation effect of glycolic acid may improve the scaly symptoms of psoriasis patients. Cover the hyperproliferation of keratinocytes in patients with psoriasis, and the abnormal thickening of the stratum corneum. Moderate exfoliation of glycolic acid may adjust the structure and function of the stratum corneum. However, there are also doubts that the stimulation of glycolic acid may exacerbate inflammation in the skin lesions of psoriasis. Because the skin of psoriasis patients is already in a state of immune activation and inflammatory response, although glycolic acid has the power of skin care, it may cause discomfort in sensitive psoriasis skin.
Furthermore, the concentration, frequency and mode of use of glycolic acid are all key factors. Low concentrations of glycolic acid or relatively mild concentrations may be beneficial to the improvement of psoriasis symptoms; high concentrations may enhance irritation or be unsuitable for psoriasis skin. And if the frequency of use is too high, it may also cause damage to the skin barrier.
In summary, the relationship between glycolic acid and psoriasis requires more rigorous clinical research and practical verification. Doctors should carefully weigh the advantages and disadvantages of glycolic acid application according to the skin condition and severity of the patient, so as to find the best treatment and care plan for the patient.