On the relationship between glycolic acid and scalp psoriasis
Husband's scalp psoriasis is a skin disease that plagues many patients. Its symptoms are mostly scalp itching, scaly hyperplasia, and even affect appearance and life. In recent years, the role of glycolic acid in such diseases has gradually attracted attention.
Glycolic acid belongs to the α-hydroxy acid class. It has unique chemical properties, and its molecules contain carboxyl and hydroxyl groups, which can participate in a variety of skin physiological processes. Many studies have shown that glycolic acid has great potential to improve the symptoms of scalp psoriasis.
First, glycolic acid has excellent keratolysis ability. During the onset of scalp psoriasis, keratinocytes proliferate rapidly, resulting in the accumulation of scales. Glycolic acid can reduce the bonding force between keratinocytes, promote the shedding of the thick stratum corneum, and improve the scalp scale condition. This process is like a spring rain moistening the soil, making the accumulated "clods" (scales) loose and disintegrate.
Second, glycolic acid can regulate the metabolism of skin cells. It can stimulate dermal fibroblasts and promote collagen and hyaluronic acid synthesis. Scalp psoriasis is often accompanied by local skin microenvironment disorders. Glycolic acid can build a strong "wall" for the scalp to resist external stimuli by regulating cell metabolism, remodeling healthy skin structure, and enhancing skin barrier function.
Third, glycolic acid may have anti-inflammatory properties. The inflammatory response of scalp psoriasis is significant, and the release of inflammatory factors triggers itching, redness and swelling. Glycolic acid can down-regulate inflammation-related signaling pathways, inhibit the expression of inflammatory factors, reduce local inflammation, such as wind inflammation, and relieve discomfort.
However, the application of glycolic acid to scalp psoriasis should also be cautious. Due to individual skin tolerances, some people may be allergic or intolerant to glycolic acid, resulting in adverse reactions such as contact dermatitis. Therefore, before use, skin sensitivity testing should be performed, and the concentration and frequency of use should be adjusted according to individual conditions.
In summary, glycolic acid has considerable prospects in the treatment of scalp psoriasis. However, in order to give full play to its effectiveness, physicians need to work closely with patients to accurately grasp the use methods and precautions, in order to bring the best treatment effect to patients and help them get rid of the pain of scalp psoriasis.