On the theory of skin peeling caused by glycolic acid
The use of glycolic acid in the skin has been widely investigated by the world. The reason why it causes skin peeling is actually related to the physiology of the skin.
The outermost layer of the skin is the stratum corneum. This layer is made up of keratinocytes tightly stacked on top of each other, which has the ability to protect the skin. Glycolic acid is an alpha-hydroxy acid, and its molecules are small and can easily penetrate into the stratum corneum.
Glycolic acid in the stratum corneum can interact with the connection structure between keratinocytes. It can reduce the adhesion of desmosomes between cells. The desmosomes are the key structures that maintain the close connection of keratinocytes. Glycolic acid decreases the adhesion of desmosomes, and the connections between keratinocytes become loose.
Over time, these loosely connected keratinocytes are easy to fall off from the surface of the skin, which is the so-called appearance of skin peeling. And glycolic acid not only affects keratinocyte connections, but also promotes skin metabolism. It can stimulate the division and differentiation of basal cells and accelerate the generation of new cells. New cells continue to move up, replacing the shed keratinocytes, which accelerates the rate of skin renewal.
However, the degree of skin peeling is also affected by many factors. The concentration of glycolic acid is one of the key factors. If the concentration is too high, the degree of skin peeling may be too severe, causing skin redness, swelling, tingling and other discomfort. The skin type of the user also has a significant impact. Sensitive skin has poor tolerance to glycolic acid, and even lower concentrations may cause more obvious skin peeling and discomfort.
Therefore, if you want to use glycolic acid to achieve the ideal skin effect, you must carefully consider the concentration and your own skin type, and gradually, in order to obtain the benefits of skin improvement and avoid the harm of excessive peeling.