A Study on the Combination of Retinoic Acid and Glycolic Acid
The medical technique is subtle, and the compatibility of medications is related to the curative effect and patient safety. The compatibility of retinoin and glycolic acid (Glycolic Acid) is a must-see.

Retinoic acid is widely used in dermatology, and it is often used to regulate the differentiation and proliferation of epidermal cells. It is effective for acne, photoaging and other diseases. Glycolic acid is an alpha-hydroxy acid, which can promote the renewal of the stratum corneum and improve the texture of the skin. It is also commonly used in cosmetic skin care.

However, the combination of the two should be treated with caution. Retinoic acid itself can cause skin irritation and increase skin sensitivity, manifested as erythema, desquamation, and burning sensation. Glycolic acid also has a certain irritation to the skin. If the two are used together, the irritating effect may be superimposed, causing skin intolerance and damaging the skin barrier.

Looking at clinical studies, some results show that when the two are used together, the probability of skin adverse reactions increases. However, some studies have shown that if used properly, such as at different times and at appropriate concentrations, it may play a synergistic effect, which can not only enhance exfoliation, improve skin condition, but also avoid the risk of excessive irritation to a certain extent.

Therefore, doctors should carefully observe the skin type and condition of the patient when taking medication. For those with strong tolerance, they may try a small range and low concentration of initial combination to closely observe the skin reaction, step by step. For sensitive skin, it is recommended to use it separately. After the skin adapts, you can decide whether to use it together or not and the specific plan.

The way of medication is like walking on thin ice, and the pros and cons must be weighed. Only by taking the well-being of the patient can the compatibility of retinoic acid and glycolic acid achieve the best curative effect and avoid the risk of adverse reactions.