When it comes to glycolic acid, which cannot be mixed with glycolic acid, it is appropriate to avoid it in nature. In the combination of various substances, it must be clear that it cannot be mixed.

Alkali substances must not be mixed with glycolic acid. Alkali is alkaline, glycolic acid is acidic. If the two meet, such as ice and fire, they will cause severe reaction. This should not only damage its chemical properties, or produce harmful things, or cause sudden changes, such as the sudden generation of heat, the sudden emergence of qi, etc., which is unfavorable to the human body and the environment.

Strong oxidizing agents should not be mixed with glycolic acid. The structure of glycolic acid makes it easy to be broken in a strong oxidizing environment. Strong oxidizing agents such as permanganate, dichromate, etc., encounter glycolic acid, or promote its rapid oxidation, causing the risk of combustion and explosion, endangering survival.

Certain metals and their salts should also not be co-located with glycolic acid. The acid of glycolic acid can erode metals, and when mixed with it, the metals are decayed, and the raw metal ions are dissolved. This not only damages the quality of glycolic acid, but also the generated metal ions may cause unexpected results in subsequent use, affecting its efficacy, or even harmful to the contacts.

And biological macromolecules such as proteins, which are not well mixed with glycolic acid. The acidity of glycolic acid can disturb the structure of proteins and cause their denaturation. If the protein structure is messed up, it will lose its inherent ability and cause great harm to the operation of the biological system.

In summary, when using glycolic acid, it is necessary to carefully observe its compatibility with various substances, so as to avoid it from being mixed, so as to ensure the integrity and efficacy.